Acetyl Coenzyme A Carboxylase Alpha Proteins

We offer Acetyl Coenzyme A Carboxylase Alpha Peptides and Acetyl Coenzyme A Carboxylase Alpha Proteins for use in common research applications: ELISA, Western Blot. Each Acetyl Coenzyme A Carboxylase Alpha Peptide and Acetyl Coenzyme A Carboxylase Alpha Protein is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our Acetyl Coenzyme A Carboxylase Alpha Peptides and Acetyl Coenzyme A Carboxylase Alpha Proteins can be used in a variety of model species: Human. Use the list below to choose the Acetyl Coenzyme A Carboxylase Alpha Peptide and Acetyl Coenzyme A Carboxylase Alpha Protein which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our Acetyl Coenzyme A Carboxylase Alpha Peptides and Proteins.

Gene ID: 31

Acetyl-CoA carboxylase 1 (ACC1) is a biotin dependent lipogenic enzyme that is highly expressed during adipogenesis. ACC1 catalyzes acetyl-CoA carboxylation, producing malonyl-CoA, a metabolite involved in energy homeostasis regulation. Malonyl-CoA is a two carbon donor in the synthesis of long-chain fatty acids and the elongation of fatty acids found in the cystol (1). ACC1 is regulated short-term by citrate, CoA, and palmitoyl-CoA through allosteric interactions. Nutrients and hormones can be both short-term (inducing reversible phosphorylations by such as AMPK) and long-term (transcription level regulation) regulators of ACC1 (2). Highly expressed in lipogenic tissues, ACC1 is found in liver, adipose, and lactating mammary gland (3). ACC1 has been implicated as a target in the development of anti-obesity drugs (4).