HDAC9 Antibodies

We offer HDAC9 Antibodies for use in common research applications: ELISA, Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot. Each HDAC9 Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our HDAC9 Antibodies can be used in a variety of model species: Human, Mouse, Rat. Use the list below to choose the HDAC9 Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Choose from our HDAC9 polyclonal antibodies and browse our HDAC9 monoclonal antibody catalog.

Gene ID: 9734

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution. HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.