p62/SQSTM1 Protein (NBP1-44490)
p62/SQSTM1 Protein
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Distributor Data...
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A170, ZIP3, PDB3, p62B, p62, p60, OSIL |
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p62/SQSTM1 Protein Summary: | | Gene: | SQSTM1 |
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| Purity: | Protein |
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| | Specificity: | This is a sequestosome 1 Protein (1-356aa). Human recombinant protein expressed in E.coli. His tag increases size to 364aa |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional p62/SQSTM1 Products p62/SQSTM1 Protein Details: | Immunogen: | MAMSYVKDDI FRIYIKEKKE CRRDHRPPCA QEAPRNMVHP NVICDGCNGP VVGTRYKCSV CPDYDLCSVC EGKGLHRGHT KLAFPSPFGH LSEGFSHSRW LRKVKHGHFG WPGWEMGPPG NWSPRPPRAG EARPGPTAES ASGPSEDPSV NFLKNVGESV AAALSPLGIE VDIDVEHGGK RSRLTPVSPE SSSTEEKSSS QPSSCCSDPS KPGGNVEGAT QSLAEQMRKI ALESEGRPEE QMESDNCSGG DDDWTHLSSK EVDPSTGELQ SLQMPESEGP SSLDPSQEGP TGLKEAALYP HLPPEADPRL IESLSQMLSM GFSDEGGWLT RLLQTKNYDI GAALDTIQYS KHPPPLLEHH HHHH |
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| Uses: | This product is useful for ELISA and SDS-Page. The purity of this protein is > 90% by SDS - PAGE. This recombinant protein was expressed in E.Coli bacteria. The endotoxin levels of this protein have not yet been determined. |
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| Dilutions: | ELISA, SDS-Page |
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| TMW: | 39.7 kDa |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Packaging: | Storage: | Store at -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: SQSTM1/p62 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. More recently, a role for SQSTM1/p62 in macroautophagic removal of intracellular protein aggregates has also been proposed. Studies involving the cellular depletion of SQSTM1/p62 have indicated a need for its association with LC3 and the aggregate proteins in order to facilitate correct formation of the autophagosome.
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Images (1) Reviews (0) Related Products (40) Exploring p62/SQSTM1
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Working with p62/SQSTM1
p62/SQSTM1 Protein Images (1) SDS-Page: SQSTM1 Protein [NBP1-44490] - SQSTM1, 39.7 kDa (364aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE |
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi
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Related ProductsLysates (3)Peptides and ProteinsPrimary Antibodies (30)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| p62/SQSTM1 Antibody | NBP1-48320 | Hu, Mu, Rt, Sh | ICC, IF, WB | (2) | (1) | | | | p62/SQSTM1 Antibody | NBP1-42822 | Hu, Mu, Rt | ICC, IF, WB | (2) | (1) | | | | p62/SQSTM1 Antibody | NBP1-42821 | Hu, Mu, Rt | ICC, IF, WB | (2) | (1) | | | | p62/SQSTM1 Antibody (2C11) | H00008878-M01 | Hu, Mu | ELISA, IF, WB | (3) | (8) | | | | p62/SQSTM1 Antibody | NBP1-49956 | Hu, Mu | IP, WB | (1) | | | | | ... and 25 more. See All » |
RNAi (1)
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