p62/SQSTM1 Antibody (NBP1-42822)
p62/SQSTM1 Antibody
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anti-Sequestosome antibody, anti-Sequestosome 1 antibody, Anti-A170 antibody, anti-ZIP3 antibody, Anti-ZIP 3 antibody, anti-ubiquitin-binding protein p62 antibody, anti-SQSTM1 antibody, anti-SQSTM 1 antibody, Anti-Sequestosome-1 antibody, anti-phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa antibody, anti-Phosphotyrosine independent ligand for the Lck SH2 domain p62 antibody, anti-PDB3 antibody, anti-PDB 3 antibody, Anti-Paget disease of bone 3 antibody, anti-p62B antibody, anti-p62 antibody, anti-p60 antibody, Anti-Oxidative stress induced like antibody, Anti-OSIL antibody, anti-ORCA antibody, anti-EBIAP antibody, anti-EBI3-associated protein of 60 kDa antibody, anti-EBI 3 associated protein of 60 kDa antibody |
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p62/SQSTM1 Antibody Summary: | | Gene: | SQSTM1 |
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| Purity: | Affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional p62/SQSTM1 Products p62/SQSTM1 Antibody Details: | Immunogen: | A synthetic peptide made to an internal region of the human p62 protein (within residues 400-450). [Swiss-Prot Q13501] |
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| Localization: | Cytoplasm. Lat endosome. Nucleus. |
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| Uses: | This SQSTM1/p62 antibody is useful for immunocytochemistry and Western blot, where a band is seen ~50 kDa. |
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| Dilutions: | Immunocytochemistry 1:50, Immunofluorescence, Western Blot 1:2000 |
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| Unit Size: | 0.1 ml (also available: 0.025 ml (sample size)) |
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| Concentration: | 1.0 mg/ml |
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| Conjugated Antibodies: | 5 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS, 30% glycerol |
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| Preservative: | 0.1% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: SQSTM1/p62 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. More recently, a role for SQSTM1/p62 in macroautophagic removal of intracellular protein aggregates has also been proposed. Studies involving the cellular depletion of SQSTM1/p62 have indicated a need for its association with LC3 and the aggregate proteins in order to facilitate correct formation of the autophagosome.
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Images (2) Reviews (0) Related Products (40) Exploring p62/SQSTM1 Working with p62/SQSTM1
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Jump to: Publications, Images, Protocols/Procedures, Ask a Question
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Working with p62/SQSTM1
p62/SQSTM1 Antibody Images (2) Immunocytochemistry: SQSTM1 Antibody [NBP1-42822] - SQSTM1 staining in of Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). |  Western Blot: SQSTM1 Antibody [NBP1-42822] - Western blot analysis of SQSTM1 in HeLa whole cell extracts using NBP1-42822. |
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Publications (1)p62/SQSTM1 Antibody Background References:- Strausberg, R.L et al. Proc. Natl. Acad. Sci. U.S.S. 99 (26) 16899-16903 (2002)
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Jump to: Conjugated Antibodies, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| p62/SQSTM1 Antibody [DyLight 650] | NBP1-42822C | Hu, Mu, Rt | ICC, IF, WB | | | | | | p62/SQSTM1 Antibody [DyLight 488] | NBP1-42822G | Hu, Mu, Rt | ICC, IF, WB | | | | | | p62/SQSTM1 Antibody [DyLight 550] | NBP1-42822R | Hu, Mu, Rt | ICC, IF, WB | | | | | | p62/SQSTM1 Antibody [Biotin] | NBP1-42822B | Hu, Mu, Rt | ICC, WB | | | | | | p62/SQSTM1 Antibody [HRP] | NBP1-42822H | Hu, Mu, Rt | ICC, WB | | | | |
Lysates (3)Peptides and ProteinsPrimary Antibodies (30)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| p62/SQSTM1 Antibody | NBP1-48320 | Hu, Mu, Rt, Sh | ICC, IF, WB | (2) | (1) | | | | p62/SQSTM1 Antibody | NBP1-42821 | Hu, Mu, Rt | ICC, IF, WB | (2) | (1) | | | | p62/SQSTM1 Antibody (2C11) | H00008878-M01 | Hu, Mu | ELISA, IF, WB | (3) | (8) | | | | p62/SQSTM1 Antibody | NBP1-49956 | Hu, Mu | IP, WB | (1) | | | | | p62/SQSTM1 Antibody | NBP1-49954 | Hu, Mu | IP, WB | (1) | | | | | ... and 25 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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