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p21 Products

p21 Primary Antibodies

We have 17 p21 Antibodies including 11 polyclonal and 6 monoclonal antibodies.

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p21 Lysates

We have 2 p21 Lysates.

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p21 Peptides and Proteins

We have 3 p21 Proteins.

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p21 RNAi

We have 2 p21 RNAi.

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Description

Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and over expression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control.

Bioinformatics

  • Uniprot
  • Product By Gene ID1026
  • Alternate Names
    • cyclin-dependent kinase inhibitor 1A (p21, Cip1)

Diseases related to p21

Discover more about diseases related to p21.

  • Neoplasms
  • Malignant Neoplasms
  • Carcinoma
  • Retinoblastoma
  • Growth Arrest
  • Cell Transformation, Neoplastic
  • Mammary Neoplasms
  • Malignant Neoplasm Of Breast
  • Malignant Paraganglionic Neoplasm
  • Leukemia
  • Adenocarcinoma
  • Malignant Tumor Of Colon
  • Carcinogenesis
  • Malignant Squamous Cell Neoplasm
  • Hyperplasia
  • Malignant Neoplasm Of Prostate
  • Prostatic Neoplasms
  • Liver Carcinoma
  • Neoplasm Metastasis
  • Colonic Neoplasms

Pathways for p21

View related products by pathway and learn more about each of the pathways below.

  • Cell Cycle
  • Cell Proliferation
  • Cell Cycle Arrest
  • Cell Growth
  • Cell Death
  • Senescence
  • S Phase
  • Induction Of Apoptosis
  • G1 Phase
  • Localization
  • Dna Repair
  • Pathogenesis
  • Dna Replication
  • Cell Differentiation
  • Cellular Senescence
  • Methylation
  • Mitosis
  • Cell Division
  • Angiogenesis
  • Rna Interference

Research Areas for p21

Find related products by research area and learn more about each of the different research areas below.

PTMs for p21

Learn more about PTMs related to p21.

  • Phosphorylation
  • Cleavage
  • Acetylation
  • Methylation
  • Dephosphorylation
  • Ubiquitination
  • Reduction
  • Demethylation
  • Deacetylation
  • Farnesylation
  • Prenylation
  • Ribosylation
  • Sumoylation
  • Phosphorothioation
  • Oxidation
  • Geranylgeranylation
  • Glycosylation
  • Myristoylation
  • Nitration
  • Biotinylation

Bioinformatics Tool for p21

Discover related pathways, diseases and genes to p21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.


 

Related p21 Blog Posts

Check out the latest blog posts on p21.
Ku70: The DNA's Mr. Fix-it
Ku70, known by several synonyms including X-ray repair cross-complementing, 5'-deoxyribose-5-phosphate lyase Ku70 protein 6, 70 kDa subunit of Ku antigen, XRCC6, and G22P1, is a 70 kDa protein that was shown to be involved in multiple cell...    Read more.
Caspase 9 and Mitochondrial Apoptosis Regulation
Caspase 9 (also termed ICE-LAP6, Mch6, Apaf-3) is a member of cysteine protease family of caspases and is encoded by the CASP9 gene in humans. Caspase-9 is involved in mitochondrial apoptosis pathway and is an initiator caspase. Pro-caspas...    Read more.
PCNA Antibodies: Marking Cell Proliferation & DNA Replication
Proliferating Cell Nuclear Antigen (PCNA), also known as the polymerase delta auxiliary protein, is a nuclear protein essential for DNA replicationas well as DNA excision and mismatch repair pathways. It has a large role in cell cycle regu...    Read more.

Read more p21 related blogs.