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The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.

Gene ID: 5460
class 5, transcription factor 1 , MGC22487 , Oct-3 , Oct-4 , OCT3Oct4 , Octamer-binding protein 3 , OTF3POU domain class 5, transcription factor 1 sli, OTF4 , POU class 5 homeobox 1 , POU-type homeodomain-containing DNA-binding protei

Histones, Bmi1 & OCT4: Investigating the Secrets of ESC Pluripotency

Epigenetic alterations have come to prominence in biomedical research. In particular, hypermethylation of CpG islands located in the promoter regions of tumor-suppressor genes ...
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Sox2 and Oct4: Roles in Embryonic Stem Cell Pluripotency

Embryonic stem (ES) cells are cells derived from the inner cell mass of the blastocyst, an early-stage embryo. ES cells are distinguished from other cells due to their pluripotency, which is the ability to differentiate ...
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An Unlikely Pairing: The SOX2 Antibody and Breast Cancer

SOX2 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, which play a vital role in embryonic development. SOX2 antibody research has identified ...
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