Mouse FasL-Strep Apoptosis Assay Products

Mouse FasL-Strep (CD95L-T4) is an engineered Murine Fas (CD95 ligand. C-Terminal fusion of the T-4-FOLDON to the extracellular FasL (CD95L) receptor-binding domain (E142-L281) results in bioactive, stable, well defined trimers in contrast to commonly used N-terminal fused coiled-coil structures1. Furthermore, fusion of a Strep-tag II C-terminal to the T4-FOLDON motif provides downstream applications like in solution cross-linking of the trimeric Fas (CD95) ligand through the monoclonal antibody StrepMAB-Immo (Cat. No. 2-1517-001) for the intensification of apoptotic activity or immobilization on Strep-Tactin coated microplates (2-1501-001) for performing a geterogeneous apoptotic assay. Recombinantly extressed and purified from HEK293 cells.