mTOR Antibody (NBP1-41830)
mTOR [Phospho-Ser2448] Antibody
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anti-Raptor antibody, anti-Rabbit polyclonal to mTOR antibody, anti-mTOR antibody, anti-Mammalian target of rapamycin antibody, anti-FRAP1 antibody, anti-FRAP antibody, anti-FK506 binding protein12-rapamycin associated protein 1 antibody, Anti-FK506 binding protein 12 rapamycin complex associated protein 1 antibody; Anti-FK506 binding protein12-rapamycin associated protein 1 antibody; Anti-FK506 binding protein12-rapamycin associated protein 2 antibody; Anti-FKBP12 rapamycin complex associ, anti-FK506 binding protein 12 rapamycin complex associated protein 1 antibody, anti-dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1) antibody, anti-Cell division cycle 25A isoform a antibody; anti-FK506 binding protein12-rapamycin associated protein 1 antibody; anti-FK506 binding protein12-rapamycin associated protein 2 antibody; anti-FRAP1 antibody; anti-
FRAP2 antibody; anti-RAFT1 antibody; an, anti-Cell division cycle 25A isoform a antibody, RAPT1 antibody, RAFT1 antibody, MTOR antibody, FRAP2 antibody, FRAP antibody, FLJ44809 antibody, anti-RAPTOR antibody, anti-RAPT1 antibody, anti-RAPT antibody, anti-Rapamycin target protein antibody, anti-RAFT1 antibody, anti-P150 target of rapamycin (TOR)-scaffold protein antibody, anti-MTOR antibody, anti-mammalian target of rapamycin antibody, anti-KIAA1303 antibody, anti-FRAP2 antibody, anti-FRAP-1 antibody, anti-FRAP1 antibody, anti-FRAP1, anti-FRAP antibody, anti-FLJ44809 antibody, anti-FKBP12 rapamycin complex associated protein antibody, anti-FK506-binding protein 12-rapamycin complex-associated protein 1 antibody, anti-FK506 binding protein12-rapamycin associated protein 2 antibody, anti-FK506 binding protein12-rapamycin associated protein 1. FK506 binding protein12-rapamycin associated protein 2. FRAP1. FRAP2. RA antibody, anti-FK506 binding protein12-rapamycin associated protein 1 antibody, anti-FK506 binding protein 12-rapamycin associated protein 1 antibody, anti-FK506 binding protein 12-rapamycin associated protein 1 (FRAP1) antibody, anti-FK506 binding protein 12 rapamycin associated protein 2 antibody, anti-FK506 binding protein 12 rapamycin associated protein 1 antibody, anti-FK506 binding protein 12 , anti-
FRAP2 antibody |
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mTOR [Phospho-Ser2448] Antibody Summary: | | Gene: | MTOR |
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| Purity: | Affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional mTOR Products mTOR [Phospho-Ser2448] Antibody Details: | Immunogen: | synthesized phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S). |
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| Modification: | Phospho-Ser2448 |
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| Uses: | This antibody is useful in Immunohistochemistry-Paraffin. |
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| Dilutions: | Immunohistochemistry-Paraffin 1:50-1:100 |
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| Unit Size: | 100 ug |
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| Concentration: | 1 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,and 50% glycerol. |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The mammalian target of rapamycin (mTOR) is a major effector of cell growth and proliferation via the regulation of protein synthesis. mTOR is composed of an N-term; 20 tandem repeats- HEAT which are implicated in protein-protein interactions and a C-term; which includes a FAT domain, a FBR domain, a kinase domain, a NDR domain and a FATC domain. The FATC domain is essential to mTOR activity and the deletion of a single amino acid from this domain abrogates the activity. mTOR can be auto-phosphorylated via its intrinsic serine/threonine kinase activity. mTOR regulates protein synthesis through the phosphorylation and inactivation of the repressor of mRNA translation 4E-BP1 and though the phosphorylation and activation of S6 kinase. RAPTOR (regulatory associated protein of TOR) is a positive regulator of TOR. Other known mediators of mTOR include PI3-K and ATK from the insulin pathway.
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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