Home » TOR/mTOR » TOR/mTOR Antibodies » TOR/mTOR Antibody [Agarose]

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

TOR/mTOR Antibody [Agarose]

 Submit a Review

Images

 

Product Details

Summary
Product Discontinued
View other related TOR/mTOR Primary Antibodies

Order Details


    • Catalog Number
      NB600-426
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

TOR/mTOR Antibody [Agarose] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 200 and 250 of human Mammalian Target of Rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTOR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunoprecipitation 1:10-1:500
Application Notes
Immunoprecipitation Suggested working dilutions: * Immunoprecipitation - 15-25 ul gel slurry per 0.1-1mg protein lysate or extract *The investigator should determine the optimal working dilution for a specific application.
Control
TOR/mTOR Overexpression Lysate

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 29728793).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TOR/mTOR Antibody [Agarose]

  • EC 2.7.11.1
  • FK506 binding protein 12-rapamycin associated protein 1
  • FK506 binding protein 12-rapamycin associated protein 2
  • FK506-binding protein 12-rapamycin complex-associated protein 1
  • FKBP12-rapamycin complex-associated protein
  • FLJ44809
  • FRAP
  • FRAP1
  • FRAP1FKBP12-rapamycin complex-associated protein 1
  • FRAP2
  • Mammalian target of rapamycin
  • mechanistic target of rapamycin (serine/threonine kinase)
  • Mechanistic target of rapamycin
  • MTOR
  • RAFT1
  • rapamycin and FKBP12 target 1
  • rapamycin associated protein FRAP2
  • Rapamycin target protein 1
  • RAPT1FKBP-rapamycin associated protein
  • serine/threonine-protein kinase mTOR
  • TOR

Background

FKBP 12 rapamycin associated protein (FRAP) is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 235 kDa protein (symbolized RAFT 1) with significant homology to the Saccharomyces cerevisiae protein TOR 1 and has been shown to associate with the immunophilin FKBP 12 in a rapamycin-dependent fashion. The FKBP 12 rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP 12 rapamycin correlated with the ability of these ligands to inhibit cell cycle progression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AKT [p Ser473]
Antibody [Unconjugate ...
AF887
Western Blot AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
Simple Western AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
Intracellular Staining by Flow Cytometry AKT [p Ser473] Antibody [Unconjugated] - Pan Specific
(52 Publications)
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, Simple Western, WB
Ribosomal Protein
S6/RPS6 Antibody
NB100-1595
Immunohistochemistry-Paraffin Ribosomal Protein S6/RPS6 Antibody
Western Blot Ribosomal Protein S6/RPS6 Antibody
Immunoprecipitation Ribosomal Protein S6/RPS6 Antibody
(1 Review)
(6 Publications)
Species: Hu, Mu
Applications: IHC,  IHC-P, IP, WB
PIK3CA Antibody -
BSA Free
NBP2-19804
Immunocytochemistry/ Immunofluorescence PIK3CA Antibody - BSA Free
Western Blot PIK3CA Antibody - BSA Free
Western Blot PIK3CA Antibody - BSA Free
(4 Publications)
Species: Hu, Mu
Applications: ICC/IF, IHC,  IHC-P, WB
PI 3-Kinase p110
gamma Antibody - BSA ...
NBP2-15071
Western Blot PI 3-Kinase p110 gamma Antibody - BSA Free
Western Blot PI 3-Kinase p110 gamma Antibody - BSA Free
Immunohistochemistry-Paraffin PI 3-Kinase p110 gamma Antibody - BSA Free
(3 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, KO, WB
PI 3-Kinase p110
beta/PIK3CB Antibody ...
MAB2686
Western Blot PI 3-Kinase p110 beta/PIK3CB Antibody (269020)
(6 Publications)
Species: Hu
Applications: WB
PI 3-Kinase p110
delta Antibody (OTI1D ...
NBP2-46404
Immunohistochemistry PI 3-Kinase p110 delta Antibody (OTI1D11)
Immunohistochemistry PI 3-Kinase p110 delta Antibody (OTI1D11)
Immunohistochemistry PI 3-Kinase p110 delta Antibody (OTI1D11)
(1 Review)
Species: Hu, Mu, Rt
Applications: IHC,  IHC-P
4EBP1 Antibody -
BSA Free
NB200-157
Western Blot 4EBP1 Antibody - BSA Free
Western Blot 4EBP1 Antibody - BSA Free
Western Blot 4EBP1 Antibody - BSA Free
(45 Publications)
Species: Hu
Applications: IHC,  IHC-P, KO, WB
Tbp7 Antibody -
BSA Free
NBP1-87799
Immunohistochemistry-Paraffin Tbp7 Antibody - BSA Free
Western Blot Tbp7 Antibody - BSA Free
Western Blot Tbp7 Antibody - BSA Free
(1 Publication)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB
p70 S6 Kinase/S6K
[p Thr389/412] Antibo ...
NB600-1049
Immunocytochemistry/ Immunofluorescence p70 S6 Kinase/S6K [p Thr389/412] Antibody - BSA Free
Immunohistochemistry p70 S6 Kinase/S6K [p Thr389/412] Antibody - BSA Free
Western Blot p70 S6 Kinase/S6K [p Thr389/412] Antibody - BSA Free
(1 Review)
(7 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB
Insulin Antibody
(182410) [Unconjugate ...
MAB1417
Immunocytochemistry Insulin Antibody (182410) [Unconjugated]
Immunohistochemistry Insulin Antibody (182410) [Unconjugated]
(31 Publications)
Species: Bv, Hu, Mu
Applications: ICC, IHC
PTEN Antibody
[Unconjugated]
AF847
Western Blot PTEN Antibody [Unconjugated]
Simple Western PTEN Antibody [Unconjugated]
Knockout Validated PTEN Antibody [Unconjugated]
(18 Publications)
Species: Hu, Mu, Rt
Applications: CyTOF-ready, IHC, ICFlow, KO, Simple Western, WB
VEGF [HRP]
DVE00
N/A VEGF [HRP]
N/A VEGF [HRP]
N/A VEGF [HRP]
(704 Publications)
Species: Hu
Applications: ELISA
EGFR Antibody
[Unconjugated]
AF231
Immunohistochemistry EGFR Antibody [Unconjugated]
Immunocytochemistry EGFR Antibody [Unconjugated]
Western Blot EGFR Antibody [Unconjugated]
(31 Publications)
Species: Hu
Applications: CyTOF-ready, Dual ISH-IHC, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, ICC, IHC, IP, Simple Western, WB
ERK2 Antibody
[Unconjugated]
AF1230
Western Blot ERK2 Antibody [Unconjugated]
Immunohistochemistry ERK2 Antibody [Unconjugated]
Knockout Validated ERK2 Antibody [Unconjugated]
(4 Publications)
Species: Hu, Mu, Rt
Applications: IHC, KO, WB
TSC2 Antibody
(SC05-59)
NBP2-67552
Flow Cytometry TSC2 Antibody (SC05-59)
Immunohistochemistry-Paraffin TSC2 Antibody (SC05-59)
Western Blot TSC2 Antibody (SC05-59)
Species: Hu, Mu, Rt
Applications: Flow, IHC,  IHC-P, WB
PYK2/FAK2 [p
Tyr402] Antibody (592 ...
MAB6210
Simple Western PYK2/FAK2 [p Tyr402] Antibody (592918) [Unconjugated]
Western Blot PYK2/FAK2 [p Tyr402] Antibody (592918) [Unconjugated]
Western Blot PYK2/FAK2 [p Tyr402] Antibody (592918) [Unconjugated]
(1 Review)
(1 Publication)
Species: Hu
Applications: Simple Western, WB
TSC1 Antibody
(OTI3A2)
NBP2-46234
Western Blot TSC1 Antibody (OTI3A2)
Western Blot TSC1 Antibody (OTI3A2)
Immunohistochemistry TSC1 Antibody (OTI3A2)
Species: Hu, Mu, Rt
Applications: IHC,  IHC-P, WB
ERK1 [p Thr202, p
Tyr204] [Biotin]
DYC1825-2
N/A ERK1 [p Thr202, p Tyr204] [Biotin]
N/A ERK1 [p Thr202, p Tyr204] [Biotin]
N/A ERK1 [p Thr202, p Tyr204] [Biotin]
(12 Publications)
Species: Hu, Mu, Rt
Applications: ELISA
eIF4E Antibody
(299910) [Unconjugate
MAB3228
Western Blot eIF4E Antibody (299910) [Unconjugated]
Immunocytochemistry eIF4E Antibody (299910) [Unconjugated]
Knockout Validated eIF4E Antibody (299910) [Unconjugated]
(3 Publications)
Species: Hu, Mu, Rt
Applications: ICC, KO, WB
TOR/mTOR Antibody
[Agarose]
NB600-426
TOR/mTOR Antibody [Agarose]
Species: Hu, Rt, Mu
Applications: IP

Publications for TOR/mTOR Antibody (NB600-426) (0)

There are no publications for TOR/mTOR Antibody (NB600-426).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TOR/mTOR Antibody (NB600-426) (0)

There are no reviews for TOR/mTOR Antibody (NB600-426). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for TOR/mTOR Antibody (NB600-426) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

TOR/mTOR Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

Additional TOR/mTOR Products

Research Areas for TOR/mTOR Antibody (NB600-426)

Find related products by research area.

Blogs on TOR/mTOR.

Check out the latest blog posts on TOR/mTOR.
Staufen1 Overabundance and the Consequent mTOR Hyperactivity in Amyotrophic Lateral Sclerosis, Spinocerebellar Ataxia Type 2, Alzheimer’s, Parkinson’s, and Huntington’s Diseases
Jamshed Arslan, Pharm D, PhD Neurodegenerative disorders involve loss of function and, ultimately, death of neurons. Selective neuronal vulnerability has been observed in a variety of neurodegenerative diseases. Fo...  Read full blog post.
mTOR Signaling and the Tumor Microenvironment
By Yoskaly Lazo-Fernandez, PhD The mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that, as a member of two distinct intracellular protein complexes, mTORC1 and mTORC2, regulates protein ...  Read full blog post.
The Many Connections Between Autophagy and Kidney Disease
By Yoskaly Lazo-Fernandez, PhD The first description of what is called today an autophagosome was given in a paper published in 1957. Its author employed electron microscopy to observe the neonatal features of mous...  Read full blog post.
Thomson Reuters Predicts 2016 Nobel Prize Winners
Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call fro...  Read full blog post.
mTOR - a central regulator of cell metabolism
The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein comp...  Read full blog post.

Contact Information

Product PDFs

  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TOR/mTOR Antibody [Agarose] and receive a gift card or discount.


Bioinformatics

Gene Symbol MTOR