Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 1675 and 1725 of human mammalian target of rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Species Reactivity:
Cross reacts with Human.
Applications:
Uses:
Western Blot and Immunoprecipitation
Dilutions:
immunoprecipitation 2 to 5 mcg/mg lysate,
Western Blot 1:2000-1:10000
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The CDT6 gene is located in an intron of this gene.
Western Blot and Immunoprecipitation: mTOR Antibody [NB100-58823] - Detection of Human mTOR on HeLa whole cell lysate using NB100-58823. mTOR was also immunoprecipitated by rabbit anti-mTOR antibodies NB100-58821 and NB100-58822.