mTOR Antibody (NB100-58821)
mTOR Antibody
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Distributor Data...
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anti-mTOR antibody, anti-RAPT antibody, anti-RAFT1 antibody, anti-mammalian target of rapamycin antibody, anti-FRAP-1 antibody, anti-FRAP1 antibody, anti-FRAP antibody, anti-FK506 binding protein 12-rapamycin associated protein 1 antibody, |
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mTOR Antibody Summary: | | Gene: | MTOR |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional mTOR Products mTOR Antibody Details: | Immunogen: | The epitope recognized by this antibody maps to a region between residue 1125 and 1175 of human mammalian target of rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475). |
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Cross reacts with Human and Mouse. |
| Uses: | Western Blot and Immunoprecipitation |
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| Dilutions: | immunoprecipitation 2 to 5 mcg/mg,
Western Blot 1:2000-1:10000 |
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| Unit Size: | 0.02 mg |
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| Concentration: | 0.2 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Tris-buffered Saline containing 0.1% BSA |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: mTOR, or FKBP12-rapamycin associated protein (FRAP), is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 245-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression.
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Images (1) Reviews (0) Related Products (45) Exploring mTOR
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Working with mTOR
mTOR Antibody Images (1) Western Blot and Immunoprecipitation: mTOR Antibody [NB100-58821] -Detection of Human and Mouse mTOR on HeLa whole cell lysate using NB100-58821. mTOR was also immunoprecipitated by rabbit anti-mTOR antibodies NB100-58822 and NB100-58823. |
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (41)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| mTOR Antibody (EP4120) | NBP1-96084 | Hu, Mu, Rt | ICC, IF, IHC-P, WB | (3) | | | | | mTOR Antibody (Y391) | NB110-56996 | Hu, Mu, Rt | FACS, ICC, IHC-P, IP, WB | (2) | (1) | | | | mTOR [p Ser2448] Antibody | NB600-607 | Hu | ELISA, IHC, IHC-P, WB | (2) | (1) | | | | mtor Antibody (EPR426(2)) | NBP1-96067 | Hu | ICC, IF, IHC-P, WB | (3) | | | | | mTOR Antibody | NBP1-02454 | Ca, Hu, Mu, Rt, Ze | ELISA, IF, IHC-P, WB | (2) | | | | | ... and 36 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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