Leptin/OB Products

Leptin/OB Antibodies

Western Blot: Leptin Antibody [NBP1-59324] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.Immunocytochemistry/Immunofluorescence: Leptin Antibody [NBP1-59324] - rat and mouse brain, 10 ug/ml.  Observed staining in cytoplasmin neurons
Species: Human, Mouse, Rat, Bovine, Canine, Equine, Goat, Porcine, Rabbit, Sheep
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Blocking/Neutralizing: Leptin/OB Antibody (44802) [MAB398] - Recombinant Human Leptin/OB (R&D Systems catalog # 398-LP) stimulates proliferation in the BaF3 mouse pro-B cell line transfected with human Leptin R in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human Leptin/OB (7.5 ng/mL) is neutralized (green line) by increasing concentrations of Human Leptin/OB Monoclonal Antibody (R&D Systems catalog # MAB398). The ND50 is typically 0.4-1.6 ug/mL.
Species: Human
Applications: B/N, ELISA(Cap)
Host: Mouse Monoclonal
Immunohistochemistry-Frozen: Leptin/OB Antibody [AF498] - Leptin/OB was detected in perfusion fixed frozen sections of mouse brain using Mouse Leptin/OB Antigen Affinity-purified Polyclonal Antibody (R&D Systems catalog # AF498) at 5 ug/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; R&D Systems catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cytoplasm.
Species: Mouse
Applications: WB, B/N, IHC, IHC-Fr, ELISA(Cap)
Host: Goat Polyclonal

Leptin/OB Antibody Pairs

Sandwich ELISA: Leptin Antibody Pair [H00003952-AP41] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA
Sandwich ELISA: Leptin Antibody Pair [H00003952-AP42] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA

Leptin/OB ELISA Kits

Leptin/OB Lysate

Leptin/OB Proteins

Species: Human
Applications: Func, PAGE
Species: Human
Applications: Func, PAGE
Species: Human
Applications: WB

Leptin/OB RNAi


Leptin, the obese (ob) gene product, is a small protein expressed in and secreted from adipose tissue of normal rodents. Studies suggest leptin acts as a circulating hormone capable of regulating body-weight homeostasis and energy balance. One possible target tissue for leptin is the hypothalamus, a proposed control center for satiety and energy expenditure. Ob gene knockout mice are characterized by several metabolic abnormalities including hyperglucocorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered central nervous system activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue. Studies show that the administration of recombinant leptin to ob knockout mice reduces food intake and increases energy expenditure.


Entrez Human
Uniprot Human
Product By Gene ID 3952
Alternate Names
  • Obese protein
  • obese, mouse, homolog of
  • leptin (obesity homolog, mouse)
  • FLJ94114
  • leptin (murine obesity homolog)
  • Obesity factor
  • leptin

Research Areas for Leptin/OB

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Diabetes Research
Lipid and Metabolism

Bioinformatics Tool for Leptin/OB

Discover related pathways, diseases and genes to Leptin/OB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.