Leptin/OB Products

Leptin/OB Antibodies

MAB398
Recombinant Human Leptin/OB (Catalog # <a class=NoLineLink href='http://www.rndsystems.com/search?keywords=398-LP'>398-LP</a>) stimulates proliferation in the BaF3 mouse pro‑B cell line transfected with human Leptin R in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human Leptin/OB (7.5 ng/mL) is neutralized (green line) by increasing concentrations of Human Leptin/OB Monoclonal Antibody (Catalog # MAB398). The ND<SUB>50</SUB> is typically 0.4-1.6 µg/mL.
Species: Human
Applications: Neut
Host: Mouse Monoclonal
AF498
Leptin/OB was detected in perfusion fixed frozen sections of mouse brain using Mouse Leptin/OB Antigen Affinity-purified Polyclonal Antibody (Catalog # AF498) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <A class=NoLineLink href=
Species: Mouse
Applications: WB, IHC, Neut
Host: Goat Polyclonal
BAM398
Species: Human
Host: Mouse Monoclonal

Leptin/OB Antibody Pairs

H00003952-AP41
Sandwich ELISA: Leptin Antibody Pair [H00003952-AP41] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA
H00003952-AP42
Sandwich ELISA: Leptin Antibody Pair [H00003952-AP42] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA

Leptin/OB ELISA Kits

Leptin/OB Lysate

Leptin/OB Proteins

NBP2-34934
SDS-Page: Human Leptin/OB Protein [NBP2-34934]
Species: Human
Applications: Func, PAGE
H00003952-P01
Species: Human
Applications: WB, ELISA, PA
NBP2-33935PEP
Species: Human
Applications: B/N, Ctrl

Leptin/OB RNAi

Leptin/OB Proteins and Enzymes

498-OB
Species: Mouse
Applications: BA
398-LP
<P align=left>Recombinant Human Leptin/OB (Catalog # 398-LP) stimulates cell proliferation in the BaF3 mouse pro-B cell line transfected with human Leptin R. The ED<SUB>50</SUB> for this effect is typically 0.4-2 ng/mL. <P align=left>1 μg/lane of Recombinant Human Leptin/OB was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 13 kDa.
Species: Human
Applications: BA
598-LP
Species: Rat
Applications: BA

Leptin/OB ELISAs

DLP00
Species: Human
MOB00
Species: Mouse, Rat
DY398
Species: Human

Leptin/OB Luminex Assay


Description

Leptin, the obese (ob) gene product, is a small protein expressed in and secreted from adipose tissue of normal rodents. Studies suggest leptin acts as a circulating hormone capable of regulating body-weight homeostasis and energy balance. One possible target tissue for leptin is the hypothalamus, a proposed control center for satiety and energy expenditure. Ob gene knockout mice are characterized by several metabolic abnormalities including hyperglucocorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered central nervous system activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue. Studies show that the administration of recombinant leptin to ob knockout mice reduces food intake and increases energy expenditure.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 3952
Alternate Names
  • Obese protein
  • obese, mouse, homolog of
  • leptin (obesity homolog, mouse)
  • FLJ94114
  • leptin (murine obesity homolog)
  • OBOBS
  • Obesity factor
  • leptin

Research Areas for Leptin/OB

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Diabetes Research
Immunology
Lipid and Metabolism

Bioinformatics Tool for Leptin/OB

Discover related pathways, diseases and genes to Leptin/OB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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