Leptin/OB Products

Leptin/OB Antibodies

MAB398
Recombinant Human Leptin/OB (Catalog # <a class=NoLineLink href='http://www.rndsystems.com/search?keywords=398-LP'>398-LP</a>) stimulates proliferation in the BaF3 mouse pro‑B cell line transfected with human Leptin R in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human Leptin/OB (7.5 ng/mL) is neutralized (green line) by increasing concentrations of Human Leptin/OB Monoclonal Antibody (Catalog # MAB398). The ND<SUB>50</SUB> is typically 0.4-1.6 µg/mL.
Species: Human
Applications: Neut
Host: Mouse Monoclonal
NBP1-59324
Western Blot: Leptin/OB Antibody [NBP1-59324] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.Immunocytochemistry: Leptin/OB Antibody [NBP1-59324] - Rat and mouse brain, 10 ug/ml.  Observed staining in cytoplasmin neurons
Species: Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Goat, Rabbit, Sheep
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal

Leptin/OB Antibody Pairs

H00003952-AP41
Sandwich ELISA: Leptin Antibody Pair [H00003952-AP41] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA
H00003952-AP42
Sandwich ELISA: Leptin Antibody Pair [H00003952-AP42] - Detection sensitivity ranging from 0.1 ng/ml to 100 ng/ml.
Species: Human
Applications: S-ELISA

Leptin/OB ELISA Kits

Leptin/OB Lysate

Leptin/OB Proteins

NBP2-34934
SDS-Page: Human Leptin/OB Protein [NBP2-34934]
Species: Human
Applications: Func, PAGE
P4064
Species: Human
Applications: Func, PAGE
NBP1-30322
Species: Human
Applications: WB

Leptin/OB RNAi


Description

Leptin, the obese (ob) gene product, is a small protein expressed in and secreted from adipose tissue of normal rodents. Studies suggest leptin acts as a circulating hormone capable of regulating body-weight homeostasis and energy balance. One possible target tissue for leptin is the hypothalamus, a proposed control center for satiety and energy expenditure. Ob gene knockout mice are characterized by several metabolic abnormalities including hyperglucocorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered central nervous system activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue. Studies show that the administration of recombinant leptin to ob knockout mice reduces food intake and increases energy expenditure.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 3952
Alternate Names
  • Obese protein
  • obese, mouse, homolog of
  • leptin (obesity homolog, mouse)
  • FLJ94114
  • leptin (murine obesity homolog)
  • OBOBS
  • Obesity factor
  • leptin

Research Areas for Leptin/OB

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Diabetes Research
Immunology
Lipid and Metabolism

Bioinformatics Tool for Leptin/OB

Discover related pathways, diseases and genes to Leptin/OB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.