The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is theligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations thatalter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play arole in hematopoiesis. (provided by RefSeq)
AGS , AHDMGC104644 , Alagille syndrome , AWS , CD339 antigen , CD339 , HJ1 , hJ1 , jagged 1 , Jagged1 , JAGL1 , protein jagged-1