GNAQ Products

Primary Antibodies

GNAQ Antibody
Species Reactivity: Human, Mouse, Rat, Bovine, Canine, Equine, Guinea Pig, Porcine, Rabbit, Zebrafish
Applications: WB
Host: Rabbit Polyclonal


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Peptides and Proteins

GNAQ Partial Recombinant Protein
H00002776-Q01
Species Reactivity: Human
Applications: WB, ELISA, PA


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GNAQ Recombinant Protein
H00002776-P01
Species Reactivity: Human
Applications: WB, ELISA, PA


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RNAi

GNAQ RNAi
H00002776-R01
Species Reactivity: Human


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Description

GNAQ, also known as Guanine nucleotide-binding protein G(q) subunit alpha, is a 359 amino acid that is 42 kDa, with subcellular nucleus location, expressed in ovary, prostate, testis and colon tissue; necessary modulator or transducer in various transmembrane signaling systems; controls B-cell selection and survival, needed to prevent B-cell-dependent autoimmunity; and also regulates chemotaxis of BM-derived neutrophils and dendritic cells. Studies on this protein have shown a relationship with the following diseases and disorders: bleeding diathesis due to gnaq deficiency, cellular blue nevus, pertussis, melanoma, acanthocytosis, fainting, polycystic ovary syndrome, trypanosomiasis, gitelman syndrome chorea, thyroid nodule, huntington's disease, thyroiditis, chagas disease, alzheimer's disease, melanoma metastasis, vasculitis, neuronitis, erythroleukemia, and heart failure. GNAQ has also shown an interaction with AGTR1, CXCR5, CRHR1, GALR2, HTR2C, and over 100 other interacting proteins in many different pathways including calcium signaling pathway, vascular smooth muscle contraction, gap junction, long-term potentiation, glutamatergic synapse, GPCR downstream signaling, hemostasis, gastrin-CREB signalling pathway via PKC and MAPK, signaling by GPCR, signal amplification.

Bioinformatics

  • Entrez
  • Uniprot
  • Product By Gene ID2776
  • Alternate Names
    • GAQG-ALPHA-q
    • guanine nucleotide binding protein (G protein), q polypeptide
    • Guanine nucleotide-binding protein alpha-q
    • guanine nucleotide-binding protein G(q) subunit alpha

Bioinformatics Tool for GNAQ

Discover related pathways, diseases and genes to GNAQ. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.