Description
Elp4 encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Bioinformatics
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- Product By Gene ID26610
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| Alternate Names |
- elongation protein 4 homolog (S. cerevisiae)
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Diseases related to Elp4
Discover more about diseases related to Elp4.
- Aniridia
- Eye Abnormalities
- Epilepsy
- Epilepsy, Rolandic
- Tissue Adhesions
- Epilepsies, Partial
- Chromosomal Rearrangement
- Benign Rolandic Epilepsy
- Apraxias
- Seizures
- Glaucoma
- Hypoplasia
- Impairment (finding)
- Malnutrition
- Melanoma
- Neurodegenerative Disorders
- Tumorigenicity
- Neoplasm Invasiveness
- Abnormal Coordination
- Unbalanced Translocation
Pathways for Elp4
View related products by pathway and learn more about each of the pathways below.
- Trna Modification
- Cell Cycle
- Cell Motility
- Exocytosis
- Brain Development
- Hypersensitivity
- Cell Proliferation
- Cell Adhesion
- Cell Migration
- Fertilization
- Dna Demethylation
- Platelet Activation
- Auxin Influx
- Cell Cycle Arrest
- Cell Division
- Cytoskeleton Organization
- Histone Acetylation
- Regulation Of Cell Cycle
- Pancreas Development
- Dna Methylation
PTMs for Elp4
Learn more about PTMs related to Elp4.
- Phosphorylation
- Acetylation
- Demethylation