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| Rabbit Polyclonal anti-Ocular Albinism 1 antibody |
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Catalog Number:
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NLS2123
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Price:
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325.00
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Background:
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Ocular albinism 1 (Nettleship-Falls; OA1) is an Orphan-U GPCR with an unknown ligand. Ocular albinism type 1 (OA1) is an inherited disorder characterized by severe reduction of visual acuity, photophobia, and retinal hypopigmentation. Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. Misfolding of the OA1 protein has been suggested as a major pathogenic mechanism in OA1. OA1 protein expression has been documented in the eye and in epidermal melanocytes. |
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Alternate Names:
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anti-ALBINISM OCULAR TYPE I antibody, anti-G protein coupled receptor 143 antibody, anti-GPR143 antibody, anti-MOA1 antibody, anti-NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody, anti-OA1 antibody, anti-Ocular albinism type 1 protein antibody, anti-Ocular albinism type 1 protein homolog antibody, anti-Ocular albinism1 Nettleship-Falls type antibody |
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Host:
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Rabbit |
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Research Areas:
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GPCR (G Protein-Coupled Receptor), IHC Grade |
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Immunogen:
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Synthetic peptide [KLH conjugated] made to the N-term extracellular |
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Epitope:
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N-terminal extracellular domain of human |
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Species Reactivity:
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Human. 45% identity and homology with mouse. |
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Uses:
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Immunohistochemistry with formalin fixed paraffin embedded tissues. Optimal working dilutions should be determined by investigator.
Other applications have not been tested |
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Dilutions:
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Suggested working dilutions *
immunohistochemistry 16 ug/ml,
Immunohistochemistry-Paraffin 16 ug/ml
* Investigator should determine optimal working dilutions. |
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Packaging:
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0.05 ml Affinity purified Rabbit antisera. |
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Concentration:
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1 mg/ml |
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Buffer:
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Phosphate buffered saline, PH 7.7 |
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Preservative:
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0.01% Sodium Azide |
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Storage:
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
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Notes:
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These products have been supplied by MBL International Corporation. Genbank accession number: NM_000273 |
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Limitations:
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This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt. |
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Gene Id:
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4935 |
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Gene System:
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GPR143 |
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