Home » Activin RIA/ALK-2/Activin Receptor Type 1 » Activin RIA/ALK-2/Activin Receptor Type 1 Antibodies » Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

 (1 Publication)
 See All Related
Submit a Review

Images

 

Product Details

Summary
Product Discontinued
View other related Activin RIA/ALK-2/Activin Receptor Type 1 Primary Antibodies

Order Details


    • Catalog Number
      NB100-79865
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Activin RIA/ALK-2/Activin Receptor Type 1 Antibody Summary

Immunogen
Peptide with sequence C-RKFKRRNQERLNPRD corresponding to internal region according to NP_001096.1.
Epitope
RKFKRRNQERLNPRD
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ACVR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 4 - 6 ug/ml
  • Immunohistochemistry-Paraffin 4 - 6 ug/ml
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 0.3 - 1 ug/ml
Application Notes
WB: Approx. 60 kDa band observed in human umbilical cord lysates (calculated MW of 57.2 kDa band according to NP_001096.1). IHC-P: Human testis shows preferential staining of cytoplasm in primary spermatocytes.
Publications
Read Publication using NB100-79865.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

  • activin A receptor, type I
  • Activin RIA
  • ActivinRIA
  • ACTRI
  • ACVR1
  • ACVR1A
  • ACVRLK2
  • ALK2
  • ALK-2
  • FOP
  • SKR1
  • TSRI

Background

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

BMP-4
[Unconjugated]
314-BP
SDS-PAGE BMP-4 [Unconjugated]
Bioactivity BMP-4 [Unconjugated]
(583 Publications)
Species: Hu
Applications: BA, BA
BMP-7
[Unconjugated]
354-BP
Bioactivity BMP-7 [Unconjugated]
Cell Culture BMP-7 [Unconjugated]
(106 Publications)
Species: Hu
Applications: BA
BMPR-IA/ALK-3
Antibody [Unconjugate
AF346
Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]
Immunohistochemistry BMPR-IA/ALK-3 Antibody [Unconjugated]
Western Blot BMPR-IA/ALK-3 Antibody [Unconjugated]
(13 Publications)
Species: Hu
Applications: IHC, WB
TGF-beta RI/ALK-5
Antibody [Unconjugate ...
AF3025
Western Blot TGF-beta RI/ALK-5 Antibody [Unconjugated]
Immunocytochemistry TGF-beta RI/ALK-5 Antibody [Unconjugated]
Western Blot TGF-beta RI/ALK-5 Antibody [Unconjugated]
(16 Publications)
Species: Hu
Applications: ELISA, ICC, WB
GARS Antibody -
BSA Free
NBP1-85533
Immunocytochemistry/ Immunofluorescence GARS Antibody - BSA Free
Immunohistochemistry-Paraffin GARS Antibody - BSA Free
Western Blot GARS Antibody - BSA Free
Species: Hu
Applications: ICC/IF, IHC,  IHC-P, WB
Smad1 Antibody
[Unconjugated]
AF2039
Immunohistochemistry Smad1 Antibody [Unconjugated]
Western Blot Smad1 Antibody [Unconjugated]
Simple Western Smad1 Antibody [Unconjugated]
(9 Publications)
Species: Hu
Applications: IHC, Simple Western, WB
BMP-2
[Unconjugated]
355-BM
Bioactivity BMP-2 [Unconjugated]
(197 Publications)
Species: Hu, Mu, Rt
Applications: BA
ALK-1 Antibody
[Unconjugated]
AF370
Western Blot ALK-1 Antibody [Unconjugated]
Western Blot ALK-1 Antibody [Unconjugated]
Western Blot ALK-1 Antibody [Unconjugated]
(1 Review)
(18 Publications)
Species: Hu
Applications: IP, WB
BMPR-IB/ALK-6
Antibody (88614) [Unc ...
MAB505
BMPR-IB/ALK-6 Antibody (88614) [Unconjugated]
(11 Publications)
Species: Hu, Mu
Applications: WB
Activin A
[Unconjugated]
338-AC
Activin A [Unconjugated]
(589 Publications)
Species: Hu, Mu, Rt
Applications: BA
Activin RIB/ALK-4
Antibody (3U6I8)
NBP3-16106
Immunohistochemistry-Paraffin Activin RIB/ALK-4 Antibody (3U6I8)
Immunohistochemistry-Paraffin Activin RIB/ALK-4 Antibody (3U6I8)
Immunohistochemistry-Paraffin Activin RIB/ALK-4 Antibody (3U6I8)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB
Activin RIIA
Antibody [Unconjugate
AF340
Immunohistochemistry Activin RIIA Antibody [Unconjugated]
(8 Publications)
Species: Hu
Applications: Block, IHC, WB
SLPI [HRP]
DPI00
N/A SLPI [HRP]
N/A SLPI [HRP]
(37 Publications)
Species: Hu
Applications: ELISA
Activin RIIB
Antibody
AF339
Immunohistochemistry Activin RIIB Antibody
Western Blot Activin RIIB Antibody
(1 Review)
(10 Publications)
Species: Hu
Applications: Block, IHC, WB
BMPR-II Antibody
[Unconjugated]
AF811
Flow Cytometry BMPR-II Antibody [Unconjugated]
Immunohistochemistry BMPR-II Antibody [Unconjugated]
(11 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC
BMP-6
[Unconjugated]
507-BP
SDS-PAGE BMP-6 [Unconjugated]
Bioactivity BMP-6 [Unconjugated]
(75 Publications)
Species: Hu
Applications: BA
Smad2/3 Antibody
[Unconjugated]
AF3797
Western Blot Smad2/3 Antibody [Unconjugated]
Chromatin Immunoprecipitation (ChIP) Smad2/3 Antibody [Unconjugated]
Immunocytochemistry Smad2/3 Antibody [Unconjugated]
(1 Review)
(26 Publications)
Species: Hu, Mu
Applications: ChIP, ICC, IHC, Simple Western, WB
TGF-beta 1
[Unconjugated]
7754-BH/CF
Bioactivity TGF-beta 1 [Unconjugated]
(53 Publications)
Species: Hu
Applications: BA
BMP-9
[Unconjugated]
3209-BP/CF
SDS-PAGE BMP-9 [Unconjugated]
Bioactivity BMP-9 [Unconjugated]
(51 Publications)
Species: Hu
Applications: BA
Smad5 [p Ser463, p
Ser465] Antibody (SY0 ...
NBP2-67394
Immunocytochemistry/ Immunofluorescence Smad5 [p Ser463, p Ser465] Antibody (SY09-03)
Immunocytochemistry/ Immunofluorescence Smad5 [p Ser463, p Ser465] Antibody (SY09-03)
Immunohistochemistry-Paraffin Smad5 [p Ser463, p Ser465] Antibody (SY09-03)
(1 Publication)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC,  IHC-P, WB

Publications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NB100-79865)(1)


Reviews for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NB100-79865) (0)

There are no reviews for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NB100-79865). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NB100-79865) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Activin RIA/ALK-2/Activin Receptor Type 1 Products

Research Areas for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (NB100-79865)

Find related products by research area.

Blogs on Activin RIA/ALK-2/Activin Receptor Type 1

There are no specific blogs for Activin RIA/ALK-2/Activin Receptor Type 1, but you can read our latest blog posts.

Contact Information

Product PDFs

  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Activin RIA/ALK-2/Activin Receptor Type 1 Antibody and receive a gift card or discount.


Bioinformatics

Gene Symbol ACVR1
Entrez
Uniprot