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Carboxyl Methyl Lysine Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB600-1337
    • Availability
      Product Discontinued

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Carboxyl Methyl Lysine Antibody Summary

Immunogen
Carboxy methyl Lysine conjugated to KLH.
Specificity
This specifically binds to Carboxy methyl Lysine modified proteins.
Clonality
Polyclonal
Host
Rabbit
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1/200 - 1/20000
  • Western Blot 1/200 - 1/20000
Publications
Read Publication using NB600-1337.

Reactivity Notes

All Species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
75mM PBS (pH 7.2), 75mM NaCl and 1.0mM EDTA
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Carboxyl Methyl Lysine Antibody

  • CML

Background

N epsilon carboxymethyl lysine (CML) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Carboxyl Methyl Lysine Antibody (NB600-1337)(1)


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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Product PDFs

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