ACOX1 antibody

Chicken Polyclonal anti-ACOX1

Catalog Number: NB100-75596	Price: $295.00

Printable Version

PDF Version

Technical Assistance

Background:

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternate Names:

anti-AOX antibody, anti-EC 1.3.3.6 antibody, anti-Palmitoyl CoA oxidase antibody, anti-SCOX antibody, anti-Straight chain acyl CoA oxidase antibody

Host:

Chicken

Immunogen:

The immunogen for this antibody was a sequence from 2a.a. to 140a.a. from ACOX1(a 660a.a. long protein)

Isotype:

IgY

Reference Sequence:

Q15067

Theoretical Molecular Weight:

74442 Da

Localization:

Peroxisomal

Species Reactivity:

This antibody is reactive against Human.
Other species have not been tested.

Uses:

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
Western Blot
* Investigator should determine optimal working dilutions.

Packaging:

0.05 mg Immunogen affinity purified Chicken antisera

Buffer:

Phosphate-Buffered Saline.

Preservative:

No Preservative

Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

General References:

[1] Fujiwara,C., Imamura,A., Hashiguchi,N., Shimozawa,N., Suzuki,Y., Kondo,N., Imanaka,T., Tsukamoto,T. and Osumi,T.
Catalase-less peroxisomes. Implication in the milder forms of peroxisome biogenesis disorder
[2] Fan,C.Y., Pan,J., Chu,R., Lee,D., Kluckman,K.D., Usuda,N., Singh,I., Yeldandi,A.V., Rao,M.S., Maeda,N. and Reddy,J.K.
Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene
[3] Watkins,P.A., McGuinness,M.C., Raymond,G.V., Hicks,B.A., Sisk,J.M., Moser,A.B. and Moser,H.W.
Distinction between peroxisomal bifunctional enzyme and acyl-CoA oxidase deficiencies
[4] Chu,R., Varanasi,U., Chu,S., Lin,Y., Usuda,N., Rao,M.S. and Reddy,J.K.
Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells
[5] Fournier,B., Saudubray,J.M., Benichou,B., Lyonnet,S., Munnich,A., Clevers,H. and Poll-The,B.T.
Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy
[6] , Varanasi U., Chu R., Chu S., Espinosa R., Lebeau M.M., Reddy J.K.
Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization.
[7] , Chu R., Varanasi U., Chu S., Lin Y., Usuda N., Rao M.S., Reddy J.K.
Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells.
[8] , Fourner B., Saudubray J.-M., Benichou B., Lyonnet S., Munnich A., Clevers H., Poll-The B.T.
Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy.
[9] , Aoyama T., Tsushima K., Souri M., Kamijo T., Suzuki Y., Shimozawa N., Orii T., Hashimoto T.
Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase.
[10] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Gene Id:

51

Gene System:

ACOX1

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ACOX1 )

Printable Version

PDF Version

Technical Assistance

Related Chicken Secondary Antibodies