ACE2 antibody

Rabbit Polyclonal anti-ACE2

Catalog Number: NB100-55873	Price: $355.00

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Background:

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Alternate Names:

anti-ACE 2 antibody, anti-ACE related carboxypeptidase antibody, anti-ACE2 antibody, anti-ACEH antibody, anti-Angiotensin converting enzyme homolog antibody, anti-Angiotensin converting enzyme like protein antibody, anti-Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody, anti-Angiotensin I converting enzyme 2 antibody, anti-DKFZP434A014 antibody

Host:

Rabbit

Immunogen:

Human ACE2 (CT) peptide.

Isotype:

IgG

Species Reactivity:

Cross reacts with Human.
Other species have not been tested.

Uses:

Western Blot and Immunohistochemistry-Paraffin
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
immunohistochemistry 2 ug/ml,
Western Blot 0.5-2 ug/ml,
Immunohistochemistry-Paraffin 2 ug/ml
* Investigator should determine optimal working dilutions.

Positive Controls:

Human kidney or human testis cell lysate can be used as positive control.
* Human Kidney Protein NB820-59231
* Human Testis Protein NB820-59266

Packaging:

0.1 mg Rabbit antisera.

Buffer:

PBS

Preservative:

0.02% Sodium Azide

Storage:

Store at 4C. Do not freeze.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

Gene Id:

59272

Gene System:

ACE2

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