ADAM15 antibody

Mouse Polyclonal anti-ADAM15 - ADAM metallopeptidase domain 15 (metargidin), MaxPab Antibody

Catalog Number: H00008751-B01	Price: $295.00

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Background:

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names:

anti-MDC15 antibody

Host:

Mouse

Immunogen:

ADAM15 (-, 1 a.a. ~ 772 a.a) full-length human protein.

Epitope:

MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCALSWRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPLNV

Species Reactivity:

Human.
Other species have not been tested.

Uses:

Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
Western Blot 1:500
ELISA
* Investigator should determine optimal working dilutions.

Packaging:

0.05 ml of mouse antisera with 50% glycerol.

Preservative:

No Preservative

Storage:

Aliquot and store at -20C or -80C.  Avoid freeze-thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

Notes:

This antibody is available only in North America and is supplied by Abnova. Lead time may be 10-14 days. The immunizing protein may also available for this product. Unit cost for the protein is $ 250 (2 ug), $ 305 (10 ug), and $ 445 (25 ug). MaxPab is a registered trademark of Abnova.

Gene Id:

8751

Gene System:

ADAM15

Western Blot analysis of ADAM15 expression in transfected 293T cell line by ADAM15 MaxPab polyclonal antibody (B01). Lane 1: ADAM15 transfected lysate(83.70 KDa). Lane 2: Non-transfected lysate.

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