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ADAM15 antibodyMouse Polyclonal anti-ADAM15 - ADAM metallopeptidase domain 15 (metargidin), MaxPab Antibody
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.Alternate Names: anti-MDC15 antibodyHost: MouseImmunogen: ADAM15 (-, 1 a.a. ~ 772 a.a) full-length human protein.Epitope: MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCALSWRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPLNVSpecies Reactivity: Human. |
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Western Blot analysis of ADAM15 expression in transfected 293T cell line by ADAM15 MaxPab polyclonal antibody (B01). Lane 1: ADAM15 transfected lysate(83.70 KDa). Lane 2: Non-transfected lysate. |