ACRV1 antibody

Mouse Polyclonal anti-ACRV1 - acrosomal vesicle protein 1, MaxPab Antibody

Catalog Number: H00000056-B01	Price: $295.00

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Background:

This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.

Alternate Names:

anti-D11S4365 antibody, anti-SPACA2 antibody

Host:

Mouse

Immunogen:

ACRV1 (AAH14588, 1 a.a. ~ 266 a.a) full-length human protein.

Epitope:

MNRFLLLMSLYLLGPARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIIC

Species Reactivity:

Human. Other species not tested.
Other species have not been tested.

Uses:

Antibody Reactive Against transfected protein with on ELISA and Western Blot. Untransfected protein used as a negative control.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
Western Blot 1:500
ELISA
* Investigator should determine optimal working dilutions.

Positive Controls:

H00000056-T01
* ACRV1 293T Cell Transient Overexpression Lysate (denatured)

Packaging:

0.05 ml of mouse antisera with 50% glycerol.

Preservative:

No Preservative

Storage:

Aliquot and store at -20C or -80C.  Avoid freeze-thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

Notes:

This antibody is available only in North America and is supplied by Abnova. Lead time may be 10-14 days. The immunizing protein may also available for this product. Unit cost for the protein is $ 250 (2 ug), $ 305 (10 ug), and $ 445 (25 ug). MaxPab is a registered trademark of Abnova.

Gene Id:

56

Gene System:

ACRV1

Western Blot analysis of ACRV1 expression in transfected 293T cell line by ACRV1 MaxPab polyclonal antibody (B01). Lane 1: ACRV1 transfected lysate(29.26 KDa). Lane 2: Non-transfected lysate.

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