- Catalog Number: NB110-68278
- Unit Size: 0.05 ml
| Gene ID | 1636 | Reference Sequence | |
| Species Summary | Hu(+) Rt(+) | Application Summary | IHC-Fr |
| Purity | Affinity purified | Host | Mouse |
| Clone | 9B9 |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Background | ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. |
| Immunogen | Human lung ACE |
| Specificity | ACE, no cross reactivity with testicular ACE. |
| Species Reactivity | This antibody is reactive against Human and Rat. Not yet tested in other species. |
| Uses | This antibody is useful for IHC for frozen sections. |
| Dilutions |
Immunohistochemistry-Frozen 1:500, |
| Concentration | 0.2 mg/ml |
| Positive Controls: | * Antigen standard for ACE (NM_152831) (transient overexpression lysate) |
| Packaging | 0.05 ml Affinity purified Mouse ascites. |
| Buffer | PBS, pH 7.4 containing 1% BSA |
| Preservative | 0.05 % sodium azide |
| Clonality | Monoclonal |
| Alternate Names | Anti-ACE 1 antibody, Anti-ACE antibody, Anti-ACE T antibody, Anti-ACE1 antibody, Anti-Angiotensin converting enzyme somatic isoform antibody, Anti-Angiotensin converting enzyme testis specific isoform antibody, Anti-Angiotensin I converting enzyme antibody, Anti-Angiotensin I converting enzyme 1 antibody, Anti-Carboxycathepsin antibody, Anti-CD 143 antibody, Anti-CD143 antibody, Anti-CD143 antigen antibody, Anti-DCP 1 antibody, Anti-DCP antibody, Anti-DCP1 antibody, Anti-Dipeptidyl carboxypeptidase 1 antibody, Anti-Kininase II antibody, Anti-MGC26566 antibody, Anti-Peptidase P antibody, Anti-Peptidyl dipeptidase A antibody, Anti-Testicular ECA antibody |
| Gene Symbol | ACE |
|
1. Mizuiri, S. et al. A. J. Kidney Diseases. 1998; 31 (2): 301-307 |



