ACOX1 Antibody
Chicken Polyclonal anti-ACOX1
Price: $295.00
  • Catalog Number: NB100-75596
  • Unit Size: 0.05 mg
Product Images
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ACOX1 ) 
Gene ID 51 Reference Sequence Q15067 
Species Summary Hu(+) Application Summary WB 
Purity Immunogen affinity purified Host Chicken 
Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Alternatively spliced transcript variants encoding different isoforms have been identified.
Isotype

IgY
Immunogen

The immunogen for this antibody was a sequence from 2a.a. to 140a.a. from ACOX1(a 660a.a. long protein)
Localization

Peroxisomal
Species Reactivity

This antibody is reactive against Human.
Uses

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Dilutions

Western Blot
Theoretical Molecular Weight

74442 Da
Packaging

0.05 mg Immunogen affinity purified Chicken antisera
Buffer

Phosphate-Buffered Saline.
Preservative

No Preservative
Alternate Names

anti-AOX antibody, anti-EC 1.3.3.6 antibody, anti-Palmitoyl CoA oxidase antibody, anti-SCOX antibody, anti-Straight chain acyl CoA oxidase antibody
Gene Symbol

ACOX1
 
 
 

[1] Fujiwara,C., Imamura,A., Hashiguchi,N., Shimozawa,N., Suzuki,Y., Kondo,N., Imanaka,T., Tsukamoto,T. and Osumi,T.

Catalase-less peroxisomes. Implication in the milder forms of peroxisome biogenesis disorder

[2] Fan,C.Y., Pan,J., Chu,R., Lee,D., Kluckman,K.D., Usuda,N., Singh,I., Yeldandi,A.V., Rao,M.S., Maeda,N. and Reddy,J.K.

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene

[3] Watkins,P.A., McGuinness,M.C., Raymond,G.V., Hicks,B.A., Sisk,J.M., Moser,A.B. and Moser,H.W.

Distinction between peroxisomal bifunctional enzyme and acyl-CoA oxidase deficiencies

[4] Chu,R., Varanasi,U., Chu,S., Lin,Y., Usuda,N., Rao,M.S. and Reddy,J.K.

Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells

[5] Fournier,B., Saudubray,J.M., Benichou,B., Lyonnet,S., Munnich,A., Clevers,H. and Poll-The,B.T.

Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy

[6] , Varanasi U., Chu R., Chu S., Espinosa R., Lebeau M.M., Reddy J.K.

Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization.

[7] , Chu R., Varanasi U., Chu S., Lin Y., Usuda N., Rao M.S., Reddy J.K.

Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells.

[8] , Fourner B., Saudubray J.-M., Benichou B., Lyonnet S., Munnich A., Clevers H., Poll-The B.T.

Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy.

[9] , Aoyama T., Tsushima K., Souri M., Kamijo T., Suzuki Y., Shimozawa N., Orii T., Hashimoto T.

Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase.

[10] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.