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- Catalog Number: NB100-55873
- Unit Size: 0.1 mg
| Gene ID | 59272 | Reference Sequence | |
| Species Summary | Hu(+) | Application Summary | IHC, WB, IHC-P |
| Purity | Host | Rabbit |
| Storage | Store at 4C. Do not freeze. |
| Background | Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function. |
| Isotype | IgG |
| Immunogen | Human ACE2 (CT) peptide. |
| Species Reactivity | Cross reacts with Human. |
| Uses | Western Blot and Immunohistochemistry-Paraffin |
| Dilutions |
immunohistochemistry 2 ug/ml, Western Blot 0.5-2 ug/ml, Immunohistochemistry-Paraffin 2 ug/ml |
| Positive Controls |
Human kidney or human testis cell lysate can be used as positive control. |
| Positive Controls: | * Human Kidney Protein NB820-59231 * Human Testis Protein NB820-59266 |
| Packaging | 0.1 mg Rabbit antisera. |
| Buffer | PBS |
| Preservative | 0.02% Sodium Azide |
| Alternate Names | anti-ACE 2 antibody, anti-ACE related carboxypeptidase antibody, anti-ACE2 antibody, anti-ACEH antibody, anti-Angiotensin converting enzyme homolog antibody, anti-Angiotensin converting enzyme like protein antibody, anti-Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody, anti-Angiotensin I converting enzyme 2 antibody, anti-DKFZP434A014 antibody |
| Gene Symbol | ACE2 |
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