ADAM15 Antibody
Mouse Polyclonal anti-ADAM15 - ADAM metallopeptidase domain 15 (metargidin), MaxPab Antibody
Price: $295.00
  • Catalog Number: H00008751-B01
  • Unit Size: 0.05 ml
Product Images
Western Blot analysis of ADAM15 expression in transfected 293T cell line by ADAM15 MaxPab polyclonal antibody (B01).<br><br>Lane 1: ADAM15 transfected lysate(83.70 KDa).<br>Lane 2: Non-transfected lysate.<br> 
Gene ID 8751 Reference Sequence  
Species Summary Hu(+) Application Summary ELISA, WB 
Purity  Host Mouse 
Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen

ADAM15 (-, 1 a.a. ~ 772 a.a) full-length human protein.

Epitope

MRLALLWALGLLGAGSPLPSWPLPNIGGTEEQQAESEKAPREPLEPQVLQDDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQGRVRGYAGSWVSICTCSGLRGLVVLTPERSYTLEQGPGDLQGPPIISRIQDLHLPGHTCALSWRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPLNV

Species Reactivity

Human.

Uses

Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Dilutions

Western Blot 1:500 ELISA

Packaging

0.05 ml of mouse antisera with 50% glycerol.

Buffer

This antibody is in antisera and the concentration is unavailable.

Preservative

No Preservative

Alternate Names

anti-MDC15 antibody

Notes

This antibody is supplied by Abnova. The immunizing protein may also available for this product. Unit cost for the protein is $ 250 (2 ug), $ 305 (10 ug), and $ 445 (25 ug). MaxPab is a registered trademark of Abnova.

Gene Symbol

ADAM15