Support: 1-888-506-6887
Worldwide flag      (Choose your country)  

c-Myc Antibody (9E11) 0.1 ml c-Myc Tag

Distributor Data

Choose a country to view pricing and purchasing information.

More on This Product

Ordering Information

Catalog Number  NB200-108
Sample Size Available
  • Availability Choose Country
  • Size(s)
  • PriceChoose Country
  • Rewards57 Points
     
  • ShippingChoose Country
  • Backed by our 100% Guarantee

Jump to Information on c-Myc Antibody (NB200-108)

c-Myc Antibody (9E11) Summary
 
Species Human, Mouse, Chicken, Yeast
Tested Applications WB, ChIP, ELISA, FLOW, IHC, IHC-Fr, IHC-P, IP
Clonality Monoclonal
Host Mouse
Gene MYC
Purity Protein A purified
Guarantee Plus All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
Innovator's Reward Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward
c-Myc Antibody (9E11) Details
 
Clone 9E11
Isotype IgG2a Kappa
Marker c-Myc Tag
Immunogen A synthetic peptide corresponding to amino acids 408-420 (AEEQKLISEEDL) of human c-Myc, conjugated to KLH. [UniProt# P01106]
Localization Nuclear
Species Reactivity
 
Human, mouse, Saccharomyces and chicken.
Reviewed Species Read 3 reviews rated 4.7  using NB200-108 in the following species:
 
Publications Read 3 publications using NB200-108 in the following species:
 
Applications/Dilutions
 
Dilutions
  • Western Blot 1:500-1:1000
  • Chromatin Immunoprecipitation 2 ug / 500 ug extract
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:200
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Frozen 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 2ug/mg lysate
Application Notes

This c-Myc antibody (clone 9E11) is useful for Flow Cytometry, ChIP, Immunoprecipitation, ELISA, Immunohistochemistry- Frozen and Paraffin and Western blot.
Positive Controls

4 Positive Controls
Directly Conjugated
Formats
DyLight 550 Labeled NB200-108R
HRP Labeled NB200-108H
DyLight 488 Labeled NB200-108G
Biotin Labeled NB200-108B
DyLight 650 Labeled NB200-108C
Learn about Custom Antibody Labeling
Reviewed Applications
Read 3 reviews rated 4.7  using
NB200-108 in the following applications:
Publications
Read 3 publications using
NB200-108 in the following applications:
Product PDFs
  Download PDF Datasheet
  Request CofA
  Request MSDS
Reviews
Earn rewards points by submitting your review for c-Myc Antibody (NB200-108).
Submit a Review
Publications
c-Myc Antibody (NB200-108) has been mentioned in at least 9 publications.
Earn rewards if you have published using c-Myc Antibody (NB200-108).
Submit a Publication
Controls & Support Products
View all related c-Myc Controls and Support Products.
Research Tools
View all c-Myc Research Tools.
Packaging, Storage & Formulations
 
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer PBS
Unit Size 0.1 ml (also available in 0.025ml (sample size))
Concentration 1.1 mg/ml
Preservative No Preservative
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt.
Bioinformatics
 
Gene Symbol MYC
Entrez
Uniprot
Alternate Names for c-Myc
 
  • avian myelocytomatosis viral oncogene homolog slid
  • BHLHE39
  • bHLHe39MRTL
  • c-Myc
  • Class E basic helix-loop-helix protein 39
  • myc proto-oncogene protein
  • myc-related translation/localization regulatory fa
  • Proto-oncogene c-Myc
  • Transcription factor p64
  • v-myc avian myelocytomatosis viral oncogene homolo
  • v-myc myelocytomatosis viral oncogene homolog (avi
Related Products by Gene
 
TP53, FOS, CDKN1A, BCL2, CCND1, JUN, RAS, MYCN, CDKN2A, MAX, EGFR, POU5F1, HRAS, TCEAL1, NSG1, EGF, ERBB2, RB1, TNF, BCL2L1
Background
 
Myc genes are a family of proto-oncogenes (L- Myc, N- Myc and C- Myc) that codes for Myc proteins which are transcriptor factors implicated in cellular proliferation, differentiation, apoptosis, metabolism, adhesion and self-renovation of tumor stem cells. Myc protein can act as transcriptional activator/repressor, and is activated via response to diverse mitogenic signals (including Wnt, Shh and EGF) and has been found to be up-regulated in several types of cancers. c-Myc participates gene transcription regulation and binds DNA in a non-specific manner, yet can specifically recognizes core sequence 5'-CAC[GA]TG-3' also. c-Myc heterodimerization with another bHLH protein namely Myc-associated factor X (MAX) is required for efficient c-Myc- DNA binding. c-Myc interacts with several proteins such as TAF1C, SPAG9, PARP10, KDM5A, KDM5B, NO66, PIM2 and with FBXW7 when phosphorylated at Thr-58/Ser-62. c-Myc activate the transcription of growth-related genes and c- Myc overexpression induce cell-cycle progression thereby implicating in a variety of cancers. Moreover, a chromosomal aberration involving c-Myc has been linked to a form of B-cell chronic lymphocytic leukemia and defective c-MYC is responsible for Burkitt lymphoma also.