This antibody reacts with an non-active center epitope on human placental and liver beta-Glucuronidase. Does not cross react with rat beta-Glucuronidase.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The antibody reacts with the Beta-Glucuronidase antigen.
Species Reactivity:
Human,Rat
Applications:
Uses:
This antibody is useful for staining of human ß-Glucuronidase in ELISA, Western blotting and frozen sections. The antibody can also be used for affinity purification of human ß-Glucuronidase. The antibody apparently reacts with the native enzyme only (onThe advised working dilution is 1:10.
Dilutions:
ELISA, Western Blot, Immunohistochemistry-Frozen
Unit Size:
1.0 ml
Concentration:
Please see the vial label for concentration.
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).[supplied by OMIM]