Bad Products | Novus Biologicals

Bad Products

Bad Primary Antibodies

35 Bad Antibodies including 25 polyclonal and 10 monoclonal antibodies. (view)

Bad Lysates

5 Bad Lysates. (view)

Bad Peptides and Proteins

3 Bad Proteins. (view)

Bad RNAi

2 Bad RNAi. (view)

Bad is a pro-apoptotic member of the Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repressor activity of Bcl-xL but not of Bcl-2. Upon dephosphorylation, activated Bad translocates to the mitochondria and displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosphorylation by growth/survival factors regulates Bad activity.

Gene ID: 572

(see alternate names)

BBC2 , BBC6 , Bcl-2-binding component 6 , Bcl-2-like protein 8 , BCL-X/BCL-2 binding protein , Bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , BCL2-antagonist of cell death protein , BCL2-associated agonist of cell death , BCL2-binding component 6 , BCL2-binding protein , Bcl2-L-8 , BCL2L8bcl2-L-8

Related Blog Posts

AKT Antibody Assays: A Complex Area with an Easy Solution

We at Novus Biologicals place a lot of emphasis on the kinase signaling pathways. Kinases, or phosphotransferase enzymes play a key role in phosphorylation signaling. Over 500 human protein kinases have so far been discovered. They play essential ...
[Read More]