ADAM15 Products

Description

ADAM15 is encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Bioinformatics

Entrez	8751 Human
Uniprot	AAH14566 Human NP_003806 Human NP_997074.1 Human O88839 Mouse Q13444 Human Q71S69 Human
Product By Gene ID	8751
Alternate Names	ADAM 15 ADAM metallopeptidase domain 15 disintegrin-like, and cysteine-rich protein 15 EC 3.4.24 MDC-15 Metargidin