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Stream the talk live



Register now to see our broadcast live from AAI on May 11th, 2015 at 12pm EST.  We are privileged to host John Nolan who is presenting his work “Measuring Extracellular Vesicles by Flow Cytometry – Challenges & Prospects”.
   
John Nolan is inarguably one of the most renowned flow cytometry researchers today.  His group develops and applies new technologies...

Signaling and Stress


The Unfolded Protein Response (UPR) is a cellular stress response related to the Endoplasmic Reticulum (ER). It is critical that a fine balance between the protein load and the folding capacity is maintained. The accumulation of unfolded or misfolded proteins in the ER leads to ER stress and activates the UPR.

Three ER proteins act as stress sensors - IRE1,...

Cell Cycle Checkpoints and Cancer

Autophagy has been shown to play a role in various physiological processes such as adaptation to starvation, cell differentiation, tumor suppression, adaptive immunity, and cell death etc. Autophagy not only preserves cellular homeostasis but also controls intracellular pathogens, ranging from unicellular organisms to humans. Autophagy therefore represents one of the most primitive examples of innate immune responses.

Autophagy has been well integrated with immune...

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