XRCC4 Antibody (NB100-343)
XRCC4 Antibody
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Distributor Data...
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Anti-DNA double-strand break repair and V(D)J recombination protein XRCC4 antibody, anti-X-ray repair cross-complementing protein 4 antibody, anti-X-ray repair complementing defective repair in Chinese hamster cells 4 antibody, anti-DNA-repair protein XRCC4 antibody, |
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XRCC4 Antibody Summary: | | Gene: | XRCC4 |
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| Purity: | Whole antisera |
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| Host: | Mouse |
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| | Specificity: | This is specific for XRCC4. |
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| Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional XRCC4 Products XRCC4 Antibody Details: | Isotype: | IgG |
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| Immunogen: | Recombinant protein encoding an amino terminalfragment of human XRCC4 purified from E. coli. |
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| Localization: | Nuclear |
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| Marker: | Nucleus Marker |
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Cross-reacts with Human. Not yet tested in other species. |
| Uses: | Western Blot: use at a dilution of 1:1000. Optimal working dilutions / concentrations should be determined by the end user.In Western blot, this antibody detects a band of approximately 46 kDa.
For IF, 1/50 in PBS:BSA, at least 30 min at room temperature. |
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| Dilutions: | immunofluorescence 1/50,
Western Blot 1:1000 |
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| Unit Size: | 0.05 ml |
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| Concentration: | This product is unpurified. Concentration is not relevant. |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | PBS [pH7.4] |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: XRCC4 (X-ray cross complementation protein-4) is an essential component for DNA double strand break repair and V(D)J recombination. The XRCC4 gene encodes a 38kDa protein that is ubiquitously expressed and contains no sequence similarity to any previously described protein. Recent experiments have shown that XRCC4 directly interacts with DNA ligase IV implicating a possible role in DNA-end joining.
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Images (2) Reviews (0) Related Products (19) Exploring XRCC4 Working with XRCC4
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Jump to: Publications, Images, Ask a Question
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Working with XRCC4
XRCC4 Antibody Images (2) Human HCT116 cells stained with NB 100-343. Photo courtesy of Patrick Calsou. |  Detection of human XRCC4 in HeLa whole cell extracts using NB 100-343. |
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Publications (1)XRCC4 Antibody Product Specific:- Jayaram S, Ketner G, Adachi N, et al. Loss of DNA ligase IV prevents recognition of DNA by double-str break repair proteins XRCC4 XLF. Nucleic Acids Res 2008;36(18):5773-5786.
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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, Secondary Antibodies
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Related ProductsPositive ControlsAntibody Pairs (2)Lysates (3)Peptides and ProteinsPrimary Antibodies (12)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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