XRCC3 Antibody (NB100-165B)

XRCC3 Antibody [Biotin]

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XRCC3 Antibody [Biotin] Summary:
Species:Hu
Applications:WB
Clonality:Polyclonal
Gene:XRCC3
Purity:Immunogen affinity purified
Host:Rabbit
Specificity:This is specific for XRCC3.
Publications:Antibody has at least 3 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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XRCC3 Antibody [Biotin] Details:
Conjugate:Biotin
Immunogen:A synthetic partial peptide of human XRCC3.
Localization:Nuclear
Species Reactivity:

100-165 reacts with human XRCC3. Other species have not been tested.

Applications:
Uses:By Western blot, this antibody recognizes a band at 38 kDa representing XRCC3. No cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D.
Dilutions:Western Blot 1:5000
Unit Size:0.1 ml
Concentration:Please see the vial label for concentration.
Positive Controls:1 Positive Controls
Conjugated Antibodies:4 Conjugated Antibodies
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:PBS
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: XRCC3
Entrez7517 (Human)
Swiss ProtO43542 (Human)
 
Background:

Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.

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Working with XRCC3

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Publications (3)

XRCC3 Antibody [Biotin] Background References:

  1. Thacker, J. A surfeit of RAD51-like genes? Trends Genet. 15(5): 166-8, 1999.
  2. Brenneman, M.A., et al. XRCC3 is required for efficient repair of chromosone breaks by homolgous recombination. Mutation Research. 459(2): 89-97, 2000. (Hamster)

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Jump to: Conjugated Antibodies, Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Positive Controls
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Other Positive Controls
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RNAi (1)
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XRCC3 in Context


Research Areas related to XRCC3 (6):
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