anti-DNA repair protein XRCC3 antibody, anti-XRCC 3 antibody, anti-X ray repair cross complementing protein 3 antibody, anti-X ray repair complementing defective repair in Chinese hamster cells 3 antibody, anti-X ray repair complementing defective repair in chinese hamster antibody,
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Human XRCC3. Does not work in mouse. Other species not tested. This antibodydoes not cross-react with Rad51B, Rad51C, Rad51D, Rad51, or XRCC2 in Western analysis.
Applications:
Uses:
By Western blot, this antibody recognizes a band at ~38 kDa. Also useful for Immunohistochemistry on paraffin-embedded sections.
Dilutions:
Immunohistochemistry-Paraffin, Western Blot 1:1000
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes.
XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.