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WWOX Antibody

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Product Details

Summary
Product Discontinued
View other related WWOX Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19649
    • Availability
      Product Discontinued

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WWOX Antibody Summary

Immunogen
Synthetic peptide, corresponding to the N-terminual of Human WWOX.
Clonality
Polyclonal
Host
Rabbit
Gene
WWOX
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of WWOX (A7) pAb in extracts from HepG2 cells.
Theoretical MW
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for WWOX Antibody

  • D16S432E
  • EC 1.1.1
  • EC 1.1.1.-
  • FOR
  • FORHHCMA56
  • FRA16D
  • Fragile site FRA16D oxidoreductase
  • SDR41C1
  • short chain dehydrogenase/reductase family 41C, member 1
  • WOX1
  • WOX1PRO0128
  • WW domain containing oxidoreductase
  • WW domain-containing oxidoreductase
  • WW domain-containing protein WWOX
  • WWOX

Background

WWOX (WW domain containing oxidoreductase) protein is a candidate tumor suppressor consisting of two WW domains that influence protein-protein interactions, and a short chain dehydrogenase (SDR) domain, that influences sex-steroid metabolism. Modulation of the WWOX gene influences esophageal squamous cell carcinogenesis and tumorigenicity of breast cancer cell lines MDA-MB-435 and T47D. The murine homolog WOX1 localizes in the mitochondria, and contains a mitochondrial targeting sequence mapping within the SDR domain. JNK1 can physically associate with WOX1 and sequester WOX1-dependent apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Bioinformatics

Gene Symbol WWOX
Entrez