Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
A synthetic peptide sequence made to a region of the human protein between residues 200-300.
Species Reactivity:
NB600-284 can be used to detect mouse, rat and human (very weakly) WNK4 protein. 100% sequence identity with rat protein.
Applications:
Uses:
This antibody is useful for Western blot where a band is seen at ~135-155 kD. No other applications have been tested. *The investigator should determine the optimal dilution for a specific application.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
WNK kinases play an important role in hypertension. WNK4 localizes to both tight junctions and to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron.