Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
A synthetic peptide sequence within the C-teminal region of human WNK1 (within the last 350 amino acids).
Localization:
Cytoplasmic
Species Reactivity:
Human, Mouse, Rat. Mouse neuroblastoma x rat dorsal root ganglia, hybridoma, F-11 lysate. There is 100% identity/homology of the immunogen with the human WNK1 protein. There is 91/99% identity/homology of the immunogen with the mouse and rat proteins.
Applications:
Uses:
By Western blot, this antibody recognizes the short form of WNK1, ~190 kDa. The theoretical molecular weight of human WNK1 is ~251 kD and rat WNK1 is ~230 kDa.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
WNK kinases play an important role in hypertension. WNK1 is a cytoplasmic protein that localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron.