VPS34 Antibody (NB110-87320C)
VPS34 Antibody [DyLight 650]
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Distributor Data...
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anti-hVps34 antibody, anti-Vps 34 antibody, anti-PtdIns 3 kinase type 3 antibody, anti-PI3K type 3 antibody, anti-PI3 kinase type 3 antibody, anti-Phosphoinositide 3 kinase class 3 antibody, anti-Phosphatidylinositol 3 kinase p100 subunit antibody, anti-Phosphatidylinositol 3 kinase class 3 antibody, anti-Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody, anti-MGC61518 antibody, anti-EC 2.7.1.137 antibody, anti-VPS-34 antibody, anti-Vps34 antibody, anti-PtdIns-3-kinase antibody, anti-PIK3C3 antibody, anti-PI3-kinase antibody, anti-PI3K antibody, anti-phosphoinositide-3-kinase antibody, anti-Phosphatidylinositol 3-kinase p100 subunit antibody, |
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VPS34 Antibody [DyLight 650] Summary: | | Gene: | PIK3C3 |
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| Purity: | Peptide affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional VPS34 Products VPS34 Antibody [DyLight 650] Details: | Conjugate: | DyLight 650 |
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| Immunogen: | Synthetic peptide made to an internal portion of the human protein (within residues 700-850). [Swiss-Prot# Q8NEB9] |
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Reacts with human, rat, mouse and porcine. 87% sequence identity with Xenopus protein. |
| Uses: | This antibody is useful for Western blot, where a band is seen ~100 kDa. |
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| Dilutions: | Western Blot 1:1000,
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| Unit Size: | 0.1 ml |
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| Concentration: | 0.2 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | 50mM sodium borate |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: VPS34, also known as phosphoinositide-3-kinase p100 subunit or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. VPS34 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. It exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. The activity of VPS34 is enhanced by manganese and can be regulated by nutrients, suggesting an important role of VPS34 in the regulation of mTOR protein synthesis. VPS34 also forms a complex with Beclin1 that promotes autophagy and tumor supression.
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Reviews (0) Related Products (16) Exploring VPS34 Working with VPS34
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Working with VPS34
VPS34 Antibody [DyLight 650] Images (0)
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Publications (2)VPS34 Antibody [DyLight 650] Background References:- Stopkova, P. et. al. 2004. Identification of PIK3C3 promoter variant associated with bipolar d
- Volinia, S. et.al. A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J. 14: 3339-3348 (2005).
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Other Positive Controls |
Lysates (2)Peptides and ProteinsPrimary Antibodies (12)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| VPS34 Antibody | NB110-87320 | Hu, Mu, Po, Rt | WB | (2) | (9) | | | | VPS34 Antibody | NBP1-86862 | Hu | IF, IHC-P, WB | (2) | | | | | VPS34 Antibody (EPR5301) | NBP1-95792 | Hu, Mu, Rt | IHC-P, WB | (2) | | | | | VPS34 Antibody | NBP1-46441 | Hu, Mu, Rt | IHC-Fr, IHC-P, WB | | | | | | VPS34 Antibody | PAB12073 | Hu, Mu, Po, Rt | WB | | | | | | ... and 7 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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