Tubulin Antibody (YL1/2) 0.1 ml Microtubule Marker

Tubulin NB600-506

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  • All Tubulin Products
  • 3 reviews  
  • 11 Publications
  • Alternate Names
     

Ordering Information: NB600-506

Catalog NumberNB600-506
  • FormUnconjugated
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Tubulin Antibody (YL1/2) Summary

 
Species Human, Mouse, Rat, Avian, Drosophila, Mammal, Primate, Yeast
Tested Applications WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP, RIA
Clonality Monoclonal
Host Rat
Gene TUBA1A
Purity Protein G purified
Guarantee Plus All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
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Tubulin Antibody (YL1/2) Details

 
Clone YL1/2
Isotype IgG2a
Marker Microtubule Marker
Epitope A linear sequence requiring an aromatic residue at the C terminus, with the two adjacent amino acids being negatively charged (represented by Gly-Gly-Tyr in Tyr-Tubulin).
Immunogen Full length native protein (purified) (S. cerevisiae).

Species Reactivity

 
Human, mouse, rat, monkey, S. cerevisiae, S. pombe, Slime moulds, Allium and birds. Expected to react with most eukaryotes due to sequence identity. Drosophila reactivity reported in scientific literature (PMID: 24019759) Other species have not been tested.
Reviewed Species Read 2 rated 5  using NB600-506 in the following species:
 
Publications Read Publications using NB600-506 in the following species:
 

Applications/Dilutions

 
Dilutions
  • Western Blot 1:5000-1:10000
  • ELISA 1:100-1:1000
  • Immunocytochemistry/Immunofluorescence 1:1000-1:10000
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Frozen 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Immunoprecipitation 1:10-1:500
  • Radioimmunoassay
Application Notes

This Tubulin Antibody (YL1/2) is useful for Western blot, Immunoprecipitation, Immunohistochemistry on frozen and paraffin-embedded sections, Immunocytochemistry/Immunofluorescence, Radioimmunoassay and ELISA. NB600-506 is ideal for use as a Western blot loading control, where a band can be seen around 50-55 kDa and as a cytoskeletal marker in Immunocytochemistry.

Other Available
Formats
7C Labeled NB600-506V2
Alexa Fluor (R) 405 Labeled NB600-506AF405
Alexa Fluor (R) 488 Labeled NB600-506AF488
Alexa Fluor (R) 647 Labeled NB600-506AF647
Alexa Fluor (R) 700 Labeled NB600-506AF700
Allophycocyanin Labeled NB600-506APC
DyLight 350 Labeled NB600-506UV
DyLight 405 Labeled NB600-506V
DyLight 405LS Labeled NB600-506V3
DyLight 488 Labeled NB600-506G
DyLight 680 Labeled NB600-506FR
DyLight 755 Labeled NB600-506IR
FITC Labeled NB600-506F
PE Labeled NB600-506PE
PerCP Labeled NB600-506PCP
Learn about Custom Antibody Labeling
Reviewed Applications
Read 1 review rated 5  using
NB600-506 in the following application:
Publications
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NB600-506 in the following applications:

Product PDFs

Reviews

Average Rating: 5 
Recent Reviews

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Publications

Tubulin Antibody (NB600-506) has been mentioned in at least 11 publications.
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Protocols and FAQs

Controls & Support Products

Research Tools

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Packaging, Storage & Formulations

 
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer Tris-glycine, 150 mM NaCl
Unit Size 0.1 ml (also available in 0.025 ml (sample size))
Concentration 1.0 mg/ml
Preservative 0.05% Sodium Azide
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

 
Gene Symbol TUBA1A

Alternate Names for Tubulin

 
  • Tubulin B-alpha-1
  • tubulin, alpha, brain-specific
  • Tubulin alpha-3 chain
  • tubulin, alpha 3
  • Alpha-tubulin 3
  • tubulin alpha-1A chain
  • FLJ25113
  • hum-a-tub2
  • B-ALPHA-1
  • TUBA3hum-a-tub1
  • LIS3
  • tubulin, alpha 1a

Related Products by Gene

Background

 
Tubulin alpha-1A chain (TUBA1A), also known as alpha-tubulin 3, tubulin B-alpha-1, B-ALPHA-1, tubulin alpha-3 chain, TUBA3, and LIS3, is a member of the tubulin family. Tubulin is the primary constituent of microtubules. Tubulin binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. The TUBA1A gene is one of three alpha tubulin genes located on chromosome 12q. TUBA1A is found on the cytoskeleton and is expressed predominantly in morphologically differentiated neurologic cells. Mutations to the TUBA1A gene cause a neurological condition called lissencephaly type 3 (LIS3). As a result of defective neuronal migration, LIS3 is characterized by microcephaly, mental retardation, and early-onset epilepsy (PMID: 22264709). The tubulin clone (YL1/2) specifically binds tyrosylated Tubulin (Tyr-Tubulin) (PMID: 6415068).