Thyroglobulin Antibody (NBP1-22921)

Thyroglobulin Antibody

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Thyroglobulin Antibody Summary:
Species:Hu
Applications:IHC-P
Clonality:Polyclonal
Gene:TG
Purity:Whole antisera
Host:Rabbit
Specificity:This reacts with human thyroglobulin containing cells in thyroid.
Publications:Antibody has at least 3 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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Thyroglobulin Antibody Details:
Immunogen:Thyroglobulin isolated from human thyroid glands.
Localization:Cytoplasmic
Species Reactivity:

Human.

Applications:
Uses:Immunohistochemistry-Paraffin Intended Use: This product is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy. Clinical interpretation of staining results should be accompanied by histological studies with proper controls. Patients? clinical histories and other relevant diagnostic tests should be utilized by a qualified person (s) when evaluating and interpreting results. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. Optimal incubation conditions should be determined by the user based upon the fixation conditions and staining system employed. Suitable for formalin fixed, paraffin embedded tissue sections.
Dilutions:Immunohistochemistry-Paraffin
Unit Size:0.5 ml
Concentration:This product is unpurified. Concentration is not relevant.
Positive Controls:1 Positive Controls
Notes:
Intended Use: This product is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy. Clinical interpretation of staining results should be accompanied by histological studies with proper controls. Patients? clinical histories and other relevant diagnostic tests should be utilized by a qualified person (s) when evaluating and interpreting results. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. Optimal incubation conditions should be determined by the user based upon the fixation conditions and staining system employed. Suitable for formalin fixed, paraffin embedded tissue sections.
Packaging:
Storage:Store at 4 °C. Do not freeze.
Preservative:Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: TG
 
Background:

Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

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Working with Thyroglobulin

Thyroglobulin Antibody Images (1)
Immunohistochemistry-Paraffin: Thyroglobulin Antibody [NBP1-22921] - Formalin fixed paraffin embedded human thyroid stained with Thyroglobulin antibody.
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Publications (3)

Thyroglobulin Antibody Background References:

  1. 3) Kastrup et al. Sc J Clin Lab Invest 45: 471, 1985.
  2. 2) Lauberg et al. Sc J Clin Lab Invest 47: 685, 1987.

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Jump to: Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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Thyroglobulin in Context


Research Areas related to Thyroglobulin (2):
Novus Explorer for Thyroglobulin gene

Try our bioinformatic tool that shows the relationships between TG and other genes, diseases, pathways and post-translational modifications.