Thyroglobulin Antibody (NB100-65183)
Thyroglobulin Antibody
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Distributor Data...
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anti-AITD 3 antibody, anti-Tgn antibody, anti-TG antibody, anti-hTG antibody, anti-AITD3 antibody |
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Thyroglobulin Antibody Summary: | | Gene: | TG |
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| Purity: | Whole antisera |
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| Host: | Rabbit |
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| | Specificity: | NB100-65183 recognizes the 670kD glycoprotein known as thyroglobulin, which is synthesized within the follicular epithelial cells of the thyroid gland. This antibody labels follicular cells in normal thyroid and colloid stored within thyroid follicles. It also labels neoplastic cells in cases of thyroid carcinoma. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Thyroglobulin Products Thyroglobulin Antibody Details: | Isotype: | IgG |
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| Immunogen: | Purified human thyroglobulin |
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| Uses: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin This product does not require protein digestion pre-treatment of paraffin sections.This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. |
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| Dilutions: | Immunohistochemistry-Frozen
Immunohistochemistry-Paraffin |
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| Unit Size: | 6.0 ml |
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| Concentration: | This product is unpurified. Concentration is not relevant. |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS, 1% Bovine Serum Albumin |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
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Jump to: Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Other Positive Controls |
Peptides and ProteinsPrimary Antibodies (25)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Thyroglobulin Antibody (EPR3614) | NBP1-40694 | Hu | IHC-P, IP, WB | (2) | | | | | Thyroglobulin Antibody (TGB04) | NB120-6228 | Ca, Hu, Mu, Rt | IHC-P | (1) | (3) | | | | Thyroglobulin Antibody (14/14) | NBP1-42112 | Hu, Mu, Rt | ELISA, IHC-P | | | | | | Thyroglobulin Antibody (RBU/01) | NBP1-22934 | Bv, GP, Gt, Hu, Po | IHC-P | | (4) | | | | Thyroglobulin Antibody (12G9) | NB110-8084 | Bv, Ca, Fe, Hu, Mu, Po, Rt | ELISA | | | | | | ... and 20 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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