Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
A synthetic peptide corresponding to residues in human Thyroglobulin was used as an immunogen.
Species Reactivity:
Reacts in Human.
Applications:
Uses:
This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation. In Western blot this antibody detects a band at approximately 300 / 294kDa.
Dilutions:
Western Blot 1:10000-20000, Immunohistochemistry-Paraffin 1:2500-5000, Immunoprecipitation 1:50
TMW:
297 kDa
Unit Size:
0.1 ml
Concentration:
Please see the vial label for concentration.
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
Antibody buffer, glycerol, and BSA.
Preservative:
Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.