Thyroglobulin Antibody (NBP1-22627)
Thyroglobulin Antibody (1D4)
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anti-AITD 3 antibody, anti-Tgn antibody, anti-TG antibody, anti-hTG antibody, anti-AITD3 antibody |
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Thyroglobulin Antibody (1D4) Summary: | | Gene: | TG |
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| Purity: | Tissue culture supernatant |
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| Host: | Mouse |
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| | Specificity: | This recognizes thyroglobulin in hyperplastic and neoplastic thyroid. Thyroglobulin is a protein of 670 kD consisting of two identical subunits. Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid. |
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| Publications: | Antibody has at least 3 Background References. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Thyroglobulin Products Thyroglobulin Antibody (1D4) Details: | Clone: | 1D4 |
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| Isotype: | IgG2a |
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| Immunogen: | BALB/C mice were immunized with purified human thyroglobulin. |
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| Localization: | Cytoplasmic |
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| Uses: | IHC-Paraffin |
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| Dilutions: | Immunohistochemistry-Paraffin 1:25-1:50 |
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| Unit Size: | 0.5 ml |
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| Concentration: | This product is unpurified. Concentration is not relevant. |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Preservative: | Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
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Reviews (0) Related Products (40) Exploring Thyroglobulin Working with Thyroglobulin
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Working with Thyroglobulin
Thyroglobulin Antibody (1D4) Images (0)
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Publications (3)Thyroglobulin Antibody (1D4) Background References:- 3) Shepherd et al. Europ J Nucl Med 10: 291, 1985.
- 2) Male et al. Immunology 54: 419, 1985.
more... - 1) Chan et al. Clin Exptl Immunol 70:516, 1987.
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Jump to: Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Other Positive Controls |
Peptides and ProteinsPrimary Antibodies (25)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Thyroglobulin Antibody (EPR3614) | NBP1-40694 | Hu | IHC-P, IP, WB | (2) | | | | | Thyroglobulin Antibody (TGB04) | NB120-6228 | Ca, Hu, Mu, Rt | IHC-P | (1) | (3) | | | | Thyroglobulin Antibody (14/14) | NBP1-42112 | Hu, Mu, Rt | ELISA, IHC-P | | | | | | Thyroglobulin Antibody (RBU/01) | NBP1-22934 | Bv, GP, Gt, Hu, Po | IHC-P | | (4) | | | | Thyroglobulin Antibody (12G9) | NB110-8084 | Bv, Ca, Fe, Hu, Mu, Po, Rt | ELISA | | | | | | ... and 20 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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