TRADD Antibody (NB100-63244)

TRADD Antibody

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TRADD Antibody Summary:
Species:Hu
Applications:ELISA, WB
Clonality:Polyclonal
Gene:TRADD
Purity:Affinity purified
Host:Goat
Specificity:NB100-63244 recognizes tumour necrosis factor receptor 1-associated death domain protein (TRADD) isoform 2, a 28kDa death domain containing protein. TRADD is expressed in most tissues. It mediates programmed cell death signalling and NF-kappa beta activation through interaction with tumour necrosis factor receptor superfamily, member 1A. By binding the adaptor protein TRAF2, TRADD reduces the recruitment of inhibitor-of-apoptosis proteins, inhibiting TRAF2 mediated apoptosis. TRADD is also involved in the Fas-induced cell death pathway via its interaction with tumour necrosis factor receptor superfamily, member-6/FAS and adaptor protein FADD/MORT1.
Publications:Antibody has at least 1 Background Reference.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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TRADD Antibody Details:
Isotype:IgG
Immunogen:Peptide sequence C-AAGQNGHEEWVG corresponding to the N-terminus of TRADD (NP_700474).
Species Reactivity:

Human. Not yet tested in other species.

Applications:
Uses:This antibody is useful for ELISA, Western Blot
Dilutions:ELISA Western Blot
Unit Size:0.1 mg
Concentration:0.5 mg/ml
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:TRIS buffered saline, pH7.3, 0.5% Bovine Serum Albumin
Preservative:0.02% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: TRADD
Entrez8717 (Human)
Swiss ProtQ15628 (Human)
 
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Publications (1)

TRADD Antibody Background References:

  1. Hsu, H. et al. (1995) The TNF receptor 1-associated protein TRADD signals cell death NF-kappa-B activation. Cell 81:495-504.

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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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TRADD in Context


Research Areas related to TRADD (3):
Novus Explorer for TRADD gene

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