TPP1 Antibody (H00001200-M01)

TPP1 Antibody (3B1)

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TPP1 Antibody (3B1) Summary:
Species:Hu
Applications:ELISA, IHC-P, WB
Clonality:Monoclonal
Gene:TPP1
Purity:IgG purified
Host:Mouse
Specificity:TPP1 - tripeptidyl peptidase I
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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TPP1 Antibody (3B1) Details:
Clone:3B1
Isotype:IgG1 Kappa
Immunogen:TPP1 (AAH14863, 195 a.a. ~ 305 a.a) partial recombinant protein with GST tag.
Epitope:GLHLGVTPSVIRKRYNLTSQDVGSGTSNNS QACAQFLEQYFHDSDLAQFMRLFGGNFAHQ ASVARVVGQQGRGRAGIEASLDVQYLMSAG ANISTWVYSSPGRHEGQEPF*
Species Reactivity:

Human. Other species not tested.

Applications:
Uses:Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Dilutions:ELISA, Immunohistochemistry-Paraffin, Western Blot 1:500
Unit Size:0.1 mg
Concentration:Please see the vial label for concentration.
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:In 1x PBS, pH 7.2
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: TPP1
Entrez1200 (Human)
Swiss ProtAAH14863 (Human)
 
Background:

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

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Working with TPP1

TPP1 Antibody (3B1) Images (3)
Immunoperoxidase of monoclonal antibody to TPP1 ( Cat # H00001200-M01 ) on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]TPP1 monoclonal antibody (M01), clone 3B1 Western Blot analysis of TPP1 expression in A-431 ( Cat # L015V1 ).
Detection limit for recombinant GST tagged TPP1 is approximately 0.1ng/ml as a capture antibody.
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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RNAi (1)
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Secondary Antibodies
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