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TIMP-1 Antibody (EPR1550)

 (3 Publications)
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Product Details

Summary
Product Discontinued
View other related TIMP-1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-96554
    • Availability
      Product Discontinued

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TIMP-1 Antibody (EPR1550) Summary

Immunogen
A synthetic peptide corresponding to residues in human TIMP-1 was used as an immunogen.
Clonality
Monoclonal
Host
Rabbit
Gene
TIMP1
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-500
  • Western Blot 1:1000-10000
Publications
Read Publications using
NBP1-96554 in the following applications:

  • WB
    2 publications

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 24349545)

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for TIMP-1 Antibody (EPR1550)

  • CLGI
  • Collagenase inhibitor
  • collagenase inhibitor)
  • EPATIMP-1
  • EPO
  • erythroid potentiating activity
  • Erythroid-potentiating activity
  • Fibroblast collagenase inhibitor
  • FLJ90373
  • HCI
  • metalloproteinase inhibitor 1
  • TIMP metallopeptidase inhibitor 1
  • TIMP1
  • TIMP-1
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • Tissue inhibitor of metalloproteinases 1

Background

Tissue inhibitor of metalloproteinase 1 (TIMP-1) is a stromal factor which forms complexes with various members of matrix metalloproteinases (MMPs) and irreversibly inactivates them. A multifunctional glycoprotein, TIMP-1 is one of the four members of TIMP family (TIMP 1-4) which exhibits 50% sequence similarity and expressed in wide variety of cells (1). TIMP-1 binds non-covalently in a 1:1 stoichiometric fashion to the active form of MMPs thereby inhibiting the proteolytic activity of these enzymes. In addition to inhibitory function, other studies have proposed growth protion, anti-apoptotic, anti- and pro-angiogenic functions for TIMP-1. TIMP-1 expression has been observed in poor clinical outcome in many cancer types, making it ideal prognostic marker in various cancer (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TIMP-1 Antibody
(EPR1550)
NBP1-96554
TIMP-1 Antibody (EPR1550)
Species: Hu, Mu, Rt
Applications: WB, IHC

Publications for TIMP-1 Antibody (NBP1-96554)(3)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.


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WB
(2)
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Rat
(2)
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Reviews for TIMP-1 Antibody (NBP1-96554) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TIMP-1 Antibody (NBP1-96554) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TIMP1
Entrez
Uniprot