TGN46 Antibody (NB110-62093) | Novus Biologicals

TGN46 Antibody (NB110-62093) (0.01 mg)

Additional Products Available View our TGN46 products. Call 303-730-1950 for recommended products	Ordering Information:
	Catalog Number	NB110-62093
	Size(s)	0.01 mg	Price:
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anti-Trans-Golgi network protein 2 antibody, anti-TGN46 antibody, anti-MGC14722; MGC-14722; TGN 38; TGN 46; TGN 48; TGN 51; TGN38; TGN-38; TGN38 homolog; TGN38 homolog; TGN48; TGN51; TGOLN 2; TGOLN2; Trans Golgi network integral membrane protein 2 [Precursor]; Trans Golgi network integral membrane protein 2; Trans Golgi netw antibody, anti-MGC14722 antibody, anti-TTGN2 antibody, anti-TTGN 2 antibody, anti-Trans Golgi network protein TGN51 antibody, anti-Trans golgi network protein 2 antibody, anti-Trans Golgi network protein (46 48 51kD isoforms) antibody, anti-Trans Golgi network integral membrane protein 2 antibody, anti-Trans Golgi network integral membrane protein 2 [Precursor] antibody, anti-trans golgi network 46 antibody, anti-TGOLN2 antibody, anti-TGOLN 2 antibody, anti-TGN51 antibody, anti-TGN48 antibody, anti-antiTGN-46 antibody, anti-TGN-46 antibody, anti-TGN46 antibody, anti-TGN38 homolog antibody, anti-TGN38 antibody, anti-TGN 51 antibody, anti-TGN 48 antibody, anti-TGN 46 antibody, anti-TGN 38 antibody, anti-Trans-Golgi network protein 2 antibody, anti-TGN46 antibody, anti-MGC14722; MGC-14722; TGN 38; TGN 46; TGN 48; TGN 51; TGN38; TGN-38; TGN38 homolog; TGN38 homolog; TGN48; TGN51; TGOLN 2; TGOLN2; Trans Golgi network integral membrane protein 2 [Precursor]; Trans Golgi network integral membrane protein 2; Trans Golgi netw antibody, anti-trans golgi network 46 antibody, anti-TGOLN2 antibody, anti-antiTGN-46 antibody, anti-TGN-46 antibody, anti-TGN 46 antibody, anti-Trans-Golgi network protein 2 antibody, anti-TGN46 antibody, anti-MGC14722; MGC-14722; TGN 38; TGN 46; TGN 48; TGN 51; TGN38; TGN-38; TGN38 homolog; TGN38 homolog; TGN48; TGN51; TGOLN 2; TGOLN2; Trans Golgi network integral membrane protein 2 [Precursor]; Trans Golgi network integral membrane protein 2; Trans Golgi netw antibody, anti-trans golgi network 46 antibody, anti-TGOLN2 antibody, anti-antiTGN-46 antibody, anti-TGN-46 antibody, anti-TGN 46 antibody, anti-MGC14722 antibody, anti-Trans-Golgi network protein TGN51 antibody, anti-Trans-Golgi network protein 2 antibody, anti-Trans-Golgi antibody, anti-TGN46 antibody, anti-TGN-38 antibody, anti-TGN38 antibody, anti-MGC14722; MGC-14722; TGN 38; TGN 46; TGN 48; TGN 51; TGN38; TGN-38; TGN38 homolog; TGN38 homolog; TGN48; TGN51; TGOLN 2; TGOLN2; Trans Golgi network integral membrane protein 2 [Precursor]; Trans Golgi network integral membrane protein 2; Trans Golgi netw antibody, anti-MGC14722 antibody, anti-TTGN2 antibody, anti-TGN51 antibody, anti-TGN48 antibody, anti-TGN46 antibody, anti-TGN38 antibody, anti-TTGN2 antibody, anti-TTGN 2 antibody, anti-Trans-Golgi network integral membrane protein 2 antibody, anti-Trans-Golgi antibody, anti-Trans Golgi network protein TGN51 antibody, anti-Trans golgi network protein 2 antibody, anti-Trans Golgi network protein (46 48 51kD isoforms) antibody, anti-Trans Golgi network integral membrane protein 2 antibody, anti-Trans Golgi network integral membrane protein 2 [Precursor] antibody, anti-trans golgi network 46 antibody, anti-trans golgi network 38 antibody, anti-TGOLN2 antibody, anti-TGOLN 2 antibody, anti-TGN51 antibody, anti-TGN48 antibody, anti-antiTGN-46 antibody, anti-TGN-46 antibody, anti-TGN46 antibody, anti-TGN38 homolog antibody, anti-TGN-38 antibody, anti-TGN38 antibody, anti-TGN 51 antibody, anti-TGN 48 antibody, anti-TGN 46 antibody, anti-TGN 38 antibody, anti-protein antibody, anti-network antibody, anti-membrane antibody, anti-integral antibody, anti-homolog antibody, anti-2 antibody, anti-Trans-Golgi network protein 2 antibody, anti-TGN46 antibody, anti-MGC14722; MGC-14722; TGN 38; TGN 46; TGN 48; TGN 51; TGN38; TGN-38; TGN38 homolog; TGN38 homolog; TGN48; TGN51; TGOLN 2; TGOLN2; Trans Golgi network integral membrane protein 2 [Precursor]; Trans Golgi network integral membrane protein 2; Trans Golgi netw antibody, anti-MGC14722 antibody, anti-TTGN2 antibody, anti-TTGN 2 antibody, anti-Trans Golgi network protein TGN51 antibody, anti-Trans golgi network protein 2 antibody, anti-Trans Golgi network protein (46 48 51kD isoforms) antibody, anti-Trans Golgi network integral membrane protein 2 antibody, anti-Trans Golgi network integral membrane protein 2 [Precursor] antibody, anti-trans golgi network 46 antibody, anti-TGOLN2 antibody, anti-TGOLN 2 antibody, anti-TGN51 antibody, anti-TGN48 antibody, anti-antiTGN-46 antibody, anti-TGN-46 antibody, anti-TGN46 antibody, anti-TGN38 homolog antibody, anti-TGN38 antibody, anti-TGN 51 antibody, anti-TGN 48 antibody, anti-TGN 46 antibody, anti-TGN 38 antibody

TGN46 Antibody Summary:

Species:	Hu, Mk	Gene:	TGOLN2
Applications:	WB, IF, IM	Purity:	IgG purified
Clonality:	Polyclonal	Host:	Sheep
Specificity:	This is specific for TGN46. TGN46 is a heavily glycosylated protein of around 110-120kDa.
Publications:	NB110-62093 has at least 8 Background References

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TGN46 Antibody Details:

Immunogen:	Antisera to TGN46 were raised by repeated immunisations of sheep with highly purified recombinant human TGN46.
Marker:	Golgi Apparatus Marker

Species Reactivity:

This antibody is reactive against human and primate. Not yet tested in other species. This is the smaller size, 10ug, and a larger size, 25ug, is available at product NB110-40767.

Applications:

Uses:	This antibody is useful for western blot, Immunofluorescence, and Immunoelectron microscopy.
Dilutions:	immunofluorescence 1:100-1:200, Western Blot 1:500-1:1000, Immunomicroscopy
Unit Size:	0.01 mg
Concentration:	0.25 mg/ml
Positive Controls:	1 Positive Controls

Packaging:

Storage:	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Buffer:	1% bovine serum albumin
Preservative:	0.09% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: TGOLN2

Entrez:	10618 (Human)

Related Genes:

Background:

Sheep anti-human TGN46 recognises a glycoprotein designated TGN46 that is localised primarily in the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network

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TGN46 Antibody Images (2)

	Immunofluorescence: TGN46 - Affinity Purified Antibody [NB110-62093] - Immunofluorescence staining of human TGN46 in 3% paraformaldehyde-fixed HeLa cells using affinity purified sheep anti-human TGN46 at 1/100. Secondary antibody was donkey anti-sheep Alexa Fluor 488.

	20ìg HeLa cell lysate was run on an SDS-PAGE gel and western blotted using affinity purified sheep anti-human TGN46 at 1/1000

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Publications (8)

TGN46 Antibody Background References:

Matas O.B. et al (2004). Association of Cdc42/N-WASP/Arp2/3 Signaling Pathway with Golgi Membranes. Traffic; 5: 838
Vuillier F. et al (2005). Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation folding defects of the mu CD79a chains. Blood; 105: 2933-2940

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Ponnambalam S. et al (1996). Primate homologues of rat TGN38: primary structure, expression functional implications. J Cell Sci; 109: 675-685
Prescott A.R. et al (1997). Distinct compartmentalization of TGN46 beta 1, 4-galactosyltransferase in HeLa cells. Eur J Cell Biol; 72: 238-246
Mills I.G. et al (2005). Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors. J Cell Biol; 70: 191-200
Marullo S. et al (2004). Homodimerization of the {beta}2-Adrenergic Receptor as a Prerequisite for Cell Surface Targeting. J Biol Chem; 279: 33390-33397
Drakesmith H. et al (2005). HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis. PNAS; 102: 11017-11022
Linstedt A.D. et al (2004). A Cycling cis-Golgi Protein Mediates Endosome-to-Golgi Traffic. Mol Biol Cell; 15: 4798-4806