SP1 Antibody (NB100-1896)
SP1 Antibody
|
This product is fully covered under the Novus guarantee+ Policy.
Click
here for details.
|
|
Distributor Data...
|
|
anti-SP 1 antibody, anti-TSFP1 antibody, anti-TSFP 1 antibody, anti-Transcription factor Sp1 antibody, anti-Specificity protein 1 antibody, anti-Sp1 transcription factor antibody, |
|
|
SP1 Antibody Summary: | | Gene: | SP1 |
|---|
| Purity: | Immunogen affinity purified |
|---|
| Host: | Goat |
|---|
| | Specificity: | This antibody is expected to recognise both reported isoforms (NP_612482.2; NP_003100.1). |
|---|
| Publications: | Antibody has at least 1 Background Reference. |
|---|
| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional SP1 Products SP1 Antibody Details: | Isotype: | IgG |
|---|
| Immunogen: | Synthetic peptide: CSRIESPNENSNNSQ, representing the internal region of the human protein according to NP_612482.2. |
|---|
Human, Mouse, Rat, Dog, Pig, Cow |
| Uses: | This antibody is useful for IHC-P. |
|---|
| Dilutions: | Peptide ELISA 1:2000 |
|---|
| TMW: | 80.7 kDa |
|---|
| Unit Size: | 0.1 mg |
|---|
| Concentration: | 0.5 mg/ml |
|---|
| Positive Controls: | 1 Positive Controls |
|---|
|
Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
|---|
| Buffer: | Tris-saline (pH7.3) with 0.5% BSA |
|---|
| Preservative: | 0.02% Sodium Azide |
|---|
| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
|---|
Background: Profound changes in patterns of gene expression can result from relatively small changes in the concentrations of sequence specific transcription factors. Synergistic interaction between factors bound to different sites within a transcriptional control region is supported by the work of Courey et al. (1989). Sp1 is a sequence specific transcription factor that recognizes GGGGCGGGGC and closely related sequences, which are often referred to as GC boxes. Sp1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. SP1 can interact with G/C rich motifs from serotonin receptor promoter. Kadonaga et al. (1987) cloned the human Sp1 cDNA and showed that it has contiguous zinc finger motifs and requires zinc for sequence specific binding to DNA.
|
Images (1) Reviews (0) Related Products (37) Exploring SP1 Working with SP1
|
Jump to: Publications, Images, Ask a Question
|
Working with SP1
SP1 Antibody Images (1) Western Blot: SP1 Antibody [NB100-1896] - NB100-1896 staining (0.3ug/ml) of Hela lysate (RIPA buffer, 30ug total protein per lane).Primary incubated for 1 hour. Detected by western blot using chemiluminescence. |
|
|
|
Publications (1)SP1 Antibody Background References:- Sakuntabhai A, Turbpaiboon C, Casademont I, Chuansumrit A, Lowhnoo T, Kajaste-Rudnitski A, Kalayanarooj SM, Tangnararatchakit K, Tangthawornchaikul N, Vasanawathana S, Chaiyaratana W, Yenchitsomanus PT, Suriyaphol P, Avirutnan P, Chokephaibulkit K, Matsuda F, Yoksan S, Jacob Y, Lathrop GM, Malasit P, Despres P, Julier C. A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet. 2005 May;37(5):507-13. Epub 2005 Apr 17.
|
|
|
|
Ask a Scientist
Can't find an answer to your question about SP1? Ask us by using live
chat or by submitting your questions below:
|
Jump to: Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
|
Related ProductsPositive ControlsPeptides and ProteinsPrimary Antibodies (35)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
|---|
| SP1 Antibody (1A5) | H00006667-M02 | Mu, Rt | ELISA, IF, IHC-P, WB | (6) | | | | | SP1 Antibody | NB600-233 | Hu | IHC-P, IP, WB | (3) | (1) | | | | SP1 Antibody (4C8) | H00006667-M03 | Hu | ELISA, IF, IHC-P, WB | (5) | | | | | SP1 Antibody (4H6) | H00006667-M01 | Hu | ELISA, IF, IHC-P, WB | (5) | | | | | SP1 Antibody | NBP1-61413 | Hu, Mu, Rt | ELISA, IF, IHC, WB | (3) | | | | | ... and 30 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
|---|
| Goat IgG Antibody [FITC] | NB710-F | Gt | ICC, IHC-P | | | | | | Goat IgG Antibody [Biotin] | NB710-B | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [Alkaline Phosphatase] | NB710-AP | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [HRP] | NB710-H | Gt | ELISA, ICC, IHC-P, WB | | (4) | | | | Goat IgG Antibody [Cy3] | NB120-6949 | Gt | ELISA, FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | See All » |
|
|
