Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 91 and 349 of Human RFC2
Localization:
Nucleus
Species Reactivity:
Tested in human. Not yet tested in any other species.
Applications:
Uses:
Western blot. The usefulness of this product in other applications has not been determined.
Dilutions:
Western Blot 1:500-1:3000
Unit Size:
0.1 ml
Concentration:
0.43 mg/ml
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
Preservative:
0.01% Thimerosal
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described.