Prostaglandin D2 Receptor Antibody (NBP1-04736)
Prostaglandin D2 Receptor Antibody
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anti-AS 1 antibody, anti-Ptgdr antibody, anti-Prostanoid DP receptor antibody, anti-Prostaglandin D2 receptor (DP) antibody, anti-PGD receptor antibody, anti-MGC49004 antibody, anti-DP antibody, anti-ASRT1 antibody, anti-ASRT 1 antibody, anti-AS1 antibody, |
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Prostaglandin D2 Receptor Antibody Summary: | | Gene: | PTGDR |
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| Purity: | Peptide affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Prostaglandin D2 Receptor Products Prostaglandin D2 Receptor Antibody Details: | Immunogen: | This polyclonal antibody was raised by immunizing rabbit with a synthetic peptide GP96 of human prostaglandin D2 receptor (DP) (PTGDR). |
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| Uses: | The antibody titer is more than 100K for ELISA. It has not been tested in the other applications. However, for the first testing, we recommend 1/5,000 dilution for ELISA, 1/1000 dilution for Western blot analysis (WB) of recombinant protein, 1/400 dilution for tissue extracts or cell lysates, 1/100 dilution for immuno-histochemistry (IHC) staining on frozen cryosections, 1/50 dilution for IHC staining on paraffin embedded sections. |
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| Dilutions: | ELISA |
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| Unit Size: | 0.1 mg |
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| Concentration: | lyoph |
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Notes: Add diH20 for desired concentration. Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | lyophilized |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
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Publications (2)Prostaglandin D2 Receptor Antibody Background References:- Iwasaki, M., Nagata, K., Takano, S., Takahashi, K., Ishii, N. Ikezawa, Z. Association of a new-type prostaglin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis. J. Invest. Dermatol. 119 (3), 609-616 (2002)
- Angeli, V., Staumont, D., Charbonnier, A.S., Hammad, H., Gosset, P., Pichavant, M., Lambrecht, B.N., Capron, M., Dombrowicz, D. Trottein, F. Activation of the D prostanoid receptor 1 regulates immune skin allergic responses. J. Immunol. 172 (6), 3822-3829 (2004)
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Related ProductsLysates (2)Peptides and ProteinsPrimary Antibodies (4)RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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